Perineural extension of cutaneous desmoplastic melanoma mimicking an intracranial malignant peripheral nerve sheath tumor

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The authors present a case illustrating the importance of obtaining a biopsy of any facial skin lesions in a patient presenting with an intracranial tumor involving the facial or trigeminal nerve. Conventional malignant melanoma metastasizes to the brain frequently and does not usually pose diagnostic difficulties. Direct intracranial spread of cutaneous melanoma is rare. In our patient, desmoplastic melanoma with perineural spread to the Meckel cave mimicked a malignant peripheral nerve sheath tumor clinically, radiographically, and histologically.

Original languageEnglish (US)
Pages (from-to)273-277
Number of pages5
JournalJournal of Neurosurgery
Volume115
Issue number2
DOIs
StatePublished - Aug 2011

Fingerprint

Neurilemmoma
Melanoma
Skin
Trigeminal Nerve
Facial Nerve
Biopsy
Brain
Neoplasms

Keywords

  • Meckel cave
  • Neurogenic sarcoma
  • Perineural spread
  • Skull base tumor
  • Spindle cell melanoma

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

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abstract = "The authors present a case illustrating the importance of obtaining a biopsy of any facial skin lesions in a patient presenting with an intracranial tumor involving the facial or trigeminal nerve. Conventional malignant melanoma metastasizes to the brain frequently and does not usually pose diagnostic difficulties. Direct intracranial spread of cutaneous melanoma is rare. In our patient, desmoplastic melanoma with perineural spread to the Meckel cave mimicked a malignant peripheral nerve sheath tumor clinically, radiographically, and histologically.",
keywords = "Meckel cave, Neurogenic sarcoma, Perineural spread, Skull base tumor, Spindle cell melanoma",
author = "Barnett, {Samuel L.} and Wells, {Michael J.} and Bruce Mickey and Hatanpaa, {Kimmo J.}",
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AU - Barnett, Samuel L.

AU - Wells, Michael J.

AU - Mickey, Bruce

AU - Hatanpaa, Kimmo J.

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AB - The authors present a case illustrating the importance of obtaining a biopsy of any facial skin lesions in a patient presenting with an intracranial tumor involving the facial or trigeminal nerve. Conventional malignant melanoma metastasizes to the brain frequently and does not usually pose diagnostic difficulties. Direct intracranial spread of cutaneous melanoma is rare. In our patient, desmoplastic melanoma with perineural spread to the Meckel cave mimicked a malignant peripheral nerve sheath tumor clinically, radiographically, and histologically.

KW - Meckel cave

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KW - Perineural spread

KW - Skull base tumor

KW - Spindle cell melanoma

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