Peripheral Neuropathy and Nerve Compression Syndromes in Burns

Amy L. Strong, Shailesh Agarwal, Paul S. Cederna, Benjamin Levi

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

Peripheral neuropathy and nerve compression syndromes lead to substantial morbidity following burn injury. Patients present with pain, paresthesias, or weakness along a specific nerve distribution or experience generalized peripheral neuropathy. The symptoms manifest at various times from within one week of hospitalization to many months after wound closure. Peripheral neuropathy may be caused by vascular occlusion of vasa nervorum, inflammation, neurotoxin production leading to apoptosis, and direct destruction of nerves from the burn injury. This article discusses the natural history, diagnosis, current treatments, and future directions for potential interventions for peripheral neuropathy and nerve compression syndromes related to burn injury.

Original languageEnglish (US)
Pages (from-to)793-803
Number of pages11
JournalClinics in Plastic Surgery
Volume44
Issue number4
DOIs
StatePublished - Oct 2017
Externally publishedYes

Keywords

  • Nerve compression syndromes
  • Peripheral nerves
  • Peripheral neuropathy

ASJC Scopus subject areas

  • Surgery

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