@article{ba6a257a2dac46e1bfdcc417c62efdd3,
title = "Peripheral sensory nerve regeneration with biodegradable materials and neurotropic factor",
author = "Hegtvedt, {Arden K.} and Zuniga, {John R} and Rath, {Erik M.}",
note = "Funding Information: Longer nerve gap distances (20–25 mm) in the rat sciatic nerve have been bridged using silicone tubular prostheses when Matrigel (Collaborative Research Inc, Bedford, MA) was placed into the lumen [63] . Matrigel is biosynthetic basement membrane material derived from a hybridoma. It contains laminin, collagen type IV collagen, heparin sulfate, proteoglycan, and enactin. Laminin, one of the principal components of Matrigel, is solubilized basement membrane that has been shown to act as substrate for nerve growth [12,23] . Nerve growth is supported by enhanced attachment and differentiation of normal and transformed anchorage-dependent epitheloid cell types. The purpose of this study was to examine the effectiveness of autogenous and alloplastic grafts as means of supporting nerve regeneration of the rabbit inferior alveolar nerve. The hypothesis that drove this study was that polyglycolic mesh entubulation and Matrigel both support nerve regeneration and the combined use provides effective nerve regeneration and sensory recovery when compared to autogenous nerve grafting. Copyright: Copyright 2018 Elsevier B.V., All rights reserved.",
year = "2002",
doi = "10.1016/S1042-3699(02)00014-6",
language = "English (US)",
volume = "14",
pages = "117--132",
journal = "Oral and Maxillofacial Surgery Clinics of North America",
issn = "1042-3699",
publisher = "W.B. Saunders Ltd",
number = "1",
}