Perirectal Infections in Patients With Small Cell Lung Cancer

Martin F. Earle, Byron E. Fossieck, Martin H. Cohen, Daniel C. Ihde, Paul A. Bunn, John D. Minna

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Fifteen anorectal infections occurred in 6.4% of 188 intensively treated patients with small cell bronchogenic carcinoma. Granulocytopenia was present at onset in 13 episodes. In eight episodes, perirectal pain preceded any objective findings by two to 11 days. Ten infections resolved with recovery from granulocytopenia, but the five abscesses required incision. Septicemia accompanied four episodes; one patient died. Early recognition and therapy of this potentially fatal infection will become increasingly important as more patients with solid tumors receive intensive therapy. (JAMA 1981;246:2464-2466).

Original languageEnglish (US)
Pages (from-to)2464-2466
Number of pages3
JournalJAMA - Journal of the American Medical Association
Volume246
Issue number21
DOIs
StatePublished - Nov 27 1981

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Small Cell Lung Carcinoma
Agranulocytosis
Infection
Small Cell Carcinoma
Bronchogenic Carcinoma
Secondary Prevention
Abscess
Sepsis
Pain
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Perirectal Infections in Patients With Small Cell Lung Cancer. / Earle, Martin F.; Fossieck, Byron E.; Cohen, Martin H.; Ihde, Daniel C.; Bunn, Paul A.; Minna, John D.

In: JAMA - Journal of the American Medical Association, Vol. 246, No. 21, 27.11.1981, p. 2464-2466.

Research output: Contribution to journalArticle

Earle, Martin F. ; Fossieck, Byron E. ; Cohen, Martin H. ; Ihde, Daniel C. ; Bunn, Paul A. ; Minna, John D. / Perirectal Infections in Patients With Small Cell Lung Cancer. In: JAMA - Journal of the American Medical Association. 1981 ; Vol. 246, No. 21. pp. 2464-2466.
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