Pertussis with severe pulmonary hypertension and leukocytosis treated with extracorporeal membrane oxygenation

Brittany B. De Berry; James E. Lynch; Dai H. Chung; Joseph B. Zwischenberger

doi:10.1007/s00383-005-1458-x

Pertussis with severe pulmonary hypertension and leukocytosis treated with extracorporeal membrane oxygenation

Brittany B. De Berry, James E. Lynch, Dai H. Chung, Joseph B. Zwischenberger

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Pertussis, or "whooping cough," is a highly communicable disease caused by the coccobacillus Bordetella pertussis. Pertussis remains one of the most common causes of death from infectious diseases worldwide. We describe a 5-week-old infant girl who presented with severe pertussis infection associated with extreme leukocytosis and required prolonged extracorporeal membrane oxygenation (ECMO). Nitric oxide therapy resolved the pulmonary hypertension, and she was successfully weaned from ECMO and discharged home after 3 months. We report successful application of ECMO for severe pertussis-induced respiratory failure despite multiple grave prognostic indicators (<1 year age, leukocytosis, pulmonary hypertension) and discuss the role of extracorporeal life support in treating pertussis.

Original language	English (US)
Pages (from-to)	692-694
Number of pages	3
Journal	Pediatric Surgery International
Volume	21
Issue number	8
DOIs	https://doi.org/10.1007/s00383-005-1458-x
State	Published - Aug 2005
Externally published	Yes

Keywords

Bordetella pertussis
ECMO
Leukocytosis
Pertussis
Pulmonary hypertension

ASJC Scopus subject areas

Surgery
Pediatrics, Perinatology, and Child Health

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10.1007/s00383-005-1458-x

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abstract = "Pertussis, or {"}whooping cough,{"} is a highly communicable disease caused by the coccobacillus Bordetella pertussis. Pertussis remains one of the most common causes of death from infectious diseases worldwide. We describe a 5-week-old infant girl who presented with severe pertussis infection associated with extreme leukocytosis and required prolonged extracorporeal membrane oxygenation (ECMO). Nitric oxide therapy resolved the pulmonary hypertension, and she was successfully weaned from ECMO and discharged home after 3 months. We report successful application of ECMO for severe pertussis-induced respiratory failure despite multiple grave prognostic indicators (<1 year age, leukocytosis, pulmonary hypertension) and discuss the role of extracorporeal life support in treating pertussis.",

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AU - De Berry, Brittany B.

AU - Lynch, James E.

AU - Chung, Dai H.

AU - Zwischenberger, Joseph B.

PY - 2005/8

Y1 - 2005/8

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AB - Pertussis, or "whooping cough," is a highly communicable disease caused by the coccobacillus Bordetella pertussis. Pertussis remains one of the most common causes of death from infectious diseases worldwide. We describe a 5-week-old infant girl who presented with severe pertussis infection associated with extreme leukocytosis and required prolonged extracorporeal membrane oxygenation (ECMO). Nitric oxide therapy resolved the pulmonary hypertension, and she was successfully weaned from ECMO and discharged home after 3 months. We report successful application of ECMO for severe pertussis-induced respiratory failure despite multiple grave prognostic indicators (<1 year age, leukocytosis, pulmonary hypertension) and discuss the role of extracorporeal life support in treating pertussis.

KW - Bordetella pertussis

KW - ECMO

KW - Leukocytosis

KW - Pertussis

KW - Pulmonary hypertension

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Pertussis with severe pulmonary hypertension and leukocytosis treated with extracorporeal membrane oxygenation

Abstract

Keywords

ASJC Scopus subject areas

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