Pertussis with severe pulmonary hypertension and leukocytosis treated with extracorporeal membrane oxygenation

Brittany B. De Berry, James E. Lynch, Dai H. Chung, Joseph B. Zwischenberger

Research output: Contribution to journalArticle

20 Scopus citations


Pertussis, or "whooping cough," is a highly communicable disease caused by the coccobacillus Bordetella pertussis. Pertussis remains one of the most common causes of death from infectious diseases worldwide. We describe a 5-week-old infant girl who presented with severe pertussis infection associated with extreme leukocytosis and required prolonged extracorporeal membrane oxygenation (ECMO). Nitric oxide therapy resolved the pulmonary hypertension, and she was successfully weaned from ECMO and discharged home after 3 months. We report successful application of ECMO for severe pertussis-induced respiratory failure despite multiple grave prognostic indicators (<1 year age, leukocytosis, pulmonary hypertension) and discuss the role of extracorporeal life support in treating pertussis.

Original languageEnglish (US)
Pages (from-to)692-694
Number of pages3
JournalPediatric Surgery International
Issue number8
Publication statusPublished - Aug 1 2005
Externally publishedYes



  • Bordetella pertussis
  • ECMO
  • Leukocytosis
  • Pertussis
  • Pulmonary hypertension

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

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