@article{d0005dd647cf488eb1b40929e0c8a6db,
title = "Pervasive roles of microRNAs in cardiovascular biology",
abstract = "First recognized as regulators of development in worms and fruitflies, microRNAs are emerging as pivotal modulators of mammalian cardiovascular development and disease. Individual microRNAs modulate the expression of collections of messenger RNA targets that often have related functions, thereby governing complex biological processes. The wideranging functions of microRNAs in the cardiovascular system have provided new perspectives on disease mechanisms and have revealed intriguing therapeutic targets, as well as diagnostics, for a variety of cardiovascular disorders.",
author = "Small, {Eric M.} and Olson, {Eric N.}",
note = "Funding Information: Acknowledgements We apologize to all colleagues whose work could not be cited owing to space restrictions. We thank J. Cabrera for artwork and J. Brown for editorial assistance. E.N.O. was supported by grants from the National Institutes of Health, the Donald W. Reynolds Center for Clinical Cardiovascular Research, the Robert A. Welch Foundation, the Fondation Leducq{\textquoteright}s Transatlantic Network for Excellence in Cardiovascular Research Program, the American Heart Association and the Jon Holden DeHaan Foundation. E.M.S. was supported by a scientist development grant from the American Heart Association.",
year = "2011",
month = jan,
day = "20",
doi = "10.1038/nature09783",
language = "English (US)",
volume = "469",
pages = "336--342",
journal = "Nature",
issn = "0028-0836",
publisher = "Nature Publishing Group",
number = "7330",
}