PET/CT of cancer patients: Part 1, pancreatic neoplasms

Elizabeth H. Dibble; Dimitrios Karantanis; Gustavo Mercier; Patrick J. Peller; Lisa A. Kachnic; Rathan M. Subramaniam

doi:10.2214/AJR.11.8182

PET/CT of cancer patients: Part 1, pancreatic neoplasms

Elizabeth H. Dibble, Dimitrios Karantanis, Gustavo Mercier, Patrick J. Peller, Lisa A. Kachnic, Rathan M. Subramaniam

Research output: Contribution to journal › Review article › peer-review

80 Scopus citations

Abstract

OBJECTIVE: Pancreatic cancer continues to have a poor prognosis despite impressive improvements in the outcomes of many other types of cancer, often because most pancreatic neoplasms are found to be unresectable at diagnosis. The purpose of this review is to provide an overview of pancreatic cancer and the role of modern imaging in its diagnosis and management with an emphasis on ¹⁸F-FDG PET/CT fusion imaging. CONCLUSION: Multimodality imaging is critical in the diagnosis and management of pancreatic cancer. PET/CT is increasingly viewed as a useful, accurate, and cost-effective modality in diagnosing and managing pancreatic cancer, but further studies are warranted. Early data suggest that contrast-enhanced PET/CT performed with modern PET/CT scanners yields high-resolution anatomic information for surgical and radiotherapeutic planning and functional information for whole-body staging in the care of patients with this disease.

Original language	English (US)
Pages (from-to)	952-967
Number of pages	16
Journal	American Journal of Roentgenology
Volume	199
Issue number	5
DOIs	https://doi.org/10.2214/AJR.11.8182
State	Published - Nov 1 2012

Keywords

CT
MRI
PET/CT
Pancreatic cancer

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.2214/AJR.11.8182

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title = "PET/CT of cancer patients: Part 1, pancreatic neoplasms",

abstract = "OBJECTIVE: Pancreatic cancer continues to have a poor prognosis despite impressive improvements in the outcomes of many other types of cancer, often because most pancreatic neoplasms are found to be unresectable at diagnosis. The purpose of this review is to provide an overview of pancreatic cancer and the role of modern imaging in its diagnosis and management with an emphasis on 18F-FDG PET/CT fusion imaging. CONCLUSION: Multimodality imaging is critical in the diagnosis and management of pancreatic cancer. PET/CT is increasingly viewed as a useful, accurate, and cost-effective modality in diagnosing and managing pancreatic cancer, but further studies are warranted. Early data suggest that contrast-enhanced PET/CT performed with modern PET/CT scanners yields high-resolution anatomic information for surgical and radiotherapeutic planning and functional information for whole-body staging in the care of patients with this disease.",

keywords = "CT, MRI, PET/CT, Pancreatic cancer",

author = "Dibble, {Elizabeth H.} and Dimitrios Karantanis and Gustavo Mercier and Peller, {Patrick J.} and Kachnic, {Lisa A.} and Subramaniam, {Rathan M.}",

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T2 - Part 1, pancreatic neoplasms

AU - Dibble, Elizabeth H.

AU - Karantanis, Dimitrios

AU - Mercier, Gustavo

AU - Peller, Patrick J.

AU - Kachnic, Lisa A.

AU - Subramaniam, Rathan M.

PY - 2012/11/1

Y1 - 2012/11/1

N2 - OBJECTIVE: Pancreatic cancer continues to have a poor prognosis despite impressive improvements in the outcomes of many other types of cancer, often because most pancreatic neoplasms are found to be unresectable at diagnosis. The purpose of this review is to provide an overview of pancreatic cancer and the role of modern imaging in its diagnosis and management with an emphasis on 18F-FDG PET/CT fusion imaging. CONCLUSION: Multimodality imaging is critical in the diagnosis and management of pancreatic cancer. PET/CT is increasingly viewed as a useful, accurate, and cost-effective modality in diagnosing and managing pancreatic cancer, but further studies are warranted. Early data suggest that contrast-enhanced PET/CT performed with modern PET/CT scanners yields high-resolution anatomic information for surgical and radiotherapeutic planning and functional information for whole-body staging in the care of patients with this disease.

AB - OBJECTIVE: Pancreatic cancer continues to have a poor prognosis despite impressive improvements in the outcomes of many other types of cancer, often because most pancreatic neoplasms are found to be unresectable at diagnosis. The purpose of this review is to provide an overview of pancreatic cancer and the role of modern imaging in its diagnosis and management with an emphasis on 18F-FDG PET/CT fusion imaging. CONCLUSION: Multimodality imaging is critical in the diagnosis and management of pancreatic cancer. PET/CT is increasingly viewed as a useful, accurate, and cost-effective modality in diagnosing and managing pancreatic cancer, but further studies are warranted. Early data suggest that contrast-enhanced PET/CT performed with modern PET/CT scanners yields high-resolution anatomic information for surgical and radiotherapeutic planning and functional information for whole-body staging in the care of patients with this disease.

KW - CT

KW - MRI

KW - PET/CT

KW - Pancreatic cancer

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PET/CT of cancer patients: Part 1, pancreatic neoplasms

Abstract

Keywords

ASJC Scopus subject areas

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