Abstract
Doses of 50 mg of ceftazidime per kg were administered intravenously to 29 newborn infants every 8 or 12 h for 3 to 5 days. Mean peak concentrations in plasma ranged from 102 to 124 μg/ml. Mean elimination half-life values ranged from 2.9 to 6.7 h and varied inversely with gestational age and plasma clearances. Peak and trough plasma bactericidal titers against an Escherichia coli and a group B streptococcus strain were at least 1:16 and 1:32, respectively.
Original language | English (US) |
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Pages (from-to) | 583-584 |
Number of pages | 2 |
Journal | Antimicrobial agents and chemotherapy |
Volume | 26 |
Issue number | 4 |
DOIs | |
State | Published - 1984 |
ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)
- Infectious Diseases