Pharmacologic management of angina and acute myocardial infarction

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A concise overview of the pharmacologic management of chronic stable angina, unstable angina, and acute myocardial infarction is presented. Nitrates, β blockers, and calcium antagonists increase exercise tolerance and decrease symptoms in patients with chronic stable angina, and aspirin may prevent myocardial infarction. In unstable angina, aspirin reduces mortality; heparin may prevent myocardial infarction; and nitrates, β blockers, calcium antagonists, and heparin may decrease angina. In acute myocardial infarction, thrombolytic therapy, aspirin, β blockers, and intravenous nitrates may decrease mortality, whereas calcium antagonists do not affect mortality. Intravenous magnesium may decrease the incidence of ventricular tachycardia, ventricular fibrillation, and mortality in patients with acute myocardial infarction. The administration of angiotensin-converting enzyme (ACE) inhibitors after the acute phase of myocardial infarction may decrease mortality and prevent reinfarction in patients with left ventricular dysfunction.

Original languageEnglish (US)
JournalThe American Journal of Cardiology
Volume72
Issue number8
DOIs
StatePublished - Sep 9 1993

Fingerprint

Myocardial Infarction
Mortality
Aspirin
Stable Angina
Unstable Angina
Nitrates
Exercise Tolerance
Thrombolytic Therapy
Left Ventricular Dysfunction
Ventricular Fibrillation
Ventricular Tachycardia
Angiotensin-Converting Enzyme Inhibitors
Magnesium
Heparin
Calcium
Incidence

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Pharmacologic management of angina and acute myocardial infarction. / Rutherford, John D.

In: The American Journal of Cardiology, Vol. 72, No. 8, 09.09.1993.

Research output: Contribution to journalArticle

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