Pharmacology and perioperative considerations for psychiatric medications

Research output: Contribution to journalReview article

Abstract

Background: Psychotropic medications are being used increasingly as analgesics and for other off-label indications for patients with and without psychiatric conditions. While the pharmacology of most of these drugs is now known, their interaction with anesthetic drugs and implications of regular use are still relatively unclear. Objective: We discuss the pharmacology, side effects, and potential medication interactions with anesthetic agents of various commonly prescribed psychotropic medications and the current recommendations regarding the continuation of these medications during the patients’ perioperative care. Method: A review of the current literature present on PubMed and Medline was conducted between the years 2000-2016. The reference lists of each selected article were also reviewed for additional sources of information. Conclusion: Psychotropic medications can be broadly divided into classes, which include antidepressants, antipsychotics, anxiolytics, mood stabilizers, and stimulants. Although most evidence suggests the continuation of these medications in the perioperative period, it is still important to determine how psychotropic medications interact with routinely used anesthetic agents and which medications should be continued and which should not be continued on an individualized basis for each patient.

Original languageEnglish (US)
Pages (from-to)169-175
Number of pages7
JournalCurrent Clinical Pharmacology
Volume12
Issue number3
DOIs
StatePublished - Aug 1 2017

Fingerprint

Psychiatry
Anesthetics
Pharmacology
Perioperative Care
Perioperative Period
Anti-Anxiety Agents
PubMed
Antidepressive Agents
Antipsychotic Agents
Analgesics
Patient Care
Pharmaceutical Preparations

Keywords

  • Anesthesia
  • Antidepressant
  • Antipsychotics
  • Mood stabilizers
  • Perioperative
  • Psychotropic
  • Stimulants

ASJC Scopus subject areas

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Pharmacology (medical)

Cite this

Pharmacology and perioperative considerations for psychiatric medications. / Sadana, Neeti; Joshi, Girish P.

In: Current Clinical Pharmacology, Vol. 12, No. 3, 01.08.2017, p. 169-175.

Research output: Contribution to journalReview article

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