Pharyngeal acid reflux in patients with single and multiple otolaryngologic disorders

Seckin O. Ulualp, Robert J. Toohill, Reza Shaker

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

OBJECTIVE: This study was designed to determine the prevalence and characteristics of pharyngeal acid reflux (PAR) events in single and multiple otolaryngologic disorders. METHODS: Sixty-seven patients with otolaryngologic symptoms and objective findings and 34 healthy control subjects were studied with an ambulatory 24-hour, 3-site pharyngoesophageal pH monitoring technique. Otolaryngologic diagnosis included isolated posterior laryngitis (PL) in 28 patients, isolated chronic rhinosinusitis (SIN) in 12, combined PL and SIN (PL+SIN) in 6, PL plus laryngotracheal stenosis (PL+LTS) in 12, and PL plus vocal cord nodules (PL+VCN) in 9. RESULTS: PAR events were documented in 68% of patients with PL, 34% of patients with SIN, 67% of patients with PL+SIN, 67% of patients with PL+LTS, 78% of patients with PL+VCN, and 21% of controls. The prevalence of PAR events in patients with isolated PL as well as those with PL combined with other disorders was significantly higher than that in patients without PL and that in controls. As a group, patients with PL had a greater number of PAR events and acid exposure time than other patients and controls. Distal and proximal esophageal reflux parameters were not significantly different among groups. CONCLUSIONS: The prevalence of PAR is significantly higher in patients with isolated PL compared to patients with other isolated otolaryngologic disorders and in controls. The prevalence of PAR in isolated otolaryngologlc disorders other than PL is similar to that in healthy controls. The prevalence of PAR is significantly higher in patients with both PL and other otolaryngologic disorders than in controls and in patients with isolated otolaryngologic disorders.

Original languageEnglish (US)
Pages (from-to)725-730
Number of pages6
JournalOtolaryngology - Head and Neck Surgery
Volume121
Issue number6
DOIs
StatePublished - 1999

Fingerprint

Laryngitis
Acids

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Pharyngeal acid reflux in patients with single and multiple otolaryngologic disorders. / Ulualp, Seckin O.; Toohill, Robert J.; Shaker, Reza.

In: Otolaryngology - Head and Neck Surgery, Vol. 121, No. 6, 1999, p. 725-730.

Research output: Contribution to journalArticle

@article{6b6865f623cd46f8b05e77941b1db907,
title = "Pharyngeal acid reflux in patients with single and multiple otolaryngologic disorders",
abstract = "OBJECTIVE: This study was designed to determine the prevalence and characteristics of pharyngeal acid reflux (PAR) events in single and multiple otolaryngologic disorders. METHODS: Sixty-seven patients with otolaryngologic symptoms and objective findings and 34 healthy control subjects were studied with an ambulatory 24-hour, 3-site pharyngoesophageal pH monitoring technique. Otolaryngologic diagnosis included isolated posterior laryngitis (PL) in 28 patients, isolated chronic rhinosinusitis (SIN) in 12, combined PL and SIN (PL+SIN) in 6, PL plus laryngotracheal stenosis (PL+LTS) in 12, and PL plus vocal cord nodules (PL+VCN) in 9. RESULTS: PAR events were documented in 68{\%} of patients with PL, 34{\%} of patients with SIN, 67{\%} of patients with PL+SIN, 67{\%} of patients with PL+LTS, 78{\%} of patients with PL+VCN, and 21{\%} of controls. The prevalence of PAR events in patients with isolated PL as well as those with PL combined with other disorders was significantly higher than that in patients without PL and that in controls. As a group, patients with PL had a greater number of PAR events and acid exposure time than other patients and controls. Distal and proximal esophageal reflux parameters were not significantly different among groups. CONCLUSIONS: The prevalence of PAR is significantly higher in patients with isolated PL compared to patients with other isolated otolaryngologic disorders and in controls. The prevalence of PAR in isolated otolaryngologlc disorders other than PL is similar to that in healthy controls. The prevalence of PAR is significantly higher in patients with both PL and other otolaryngologic disorders than in controls and in patients with isolated otolaryngologic disorders.",
author = "Ulualp, {Seckin O.} and Toohill, {Robert J.} and Reza Shaker",
year = "1999",
doi = "10.1053/hn.1999.v121.a98010",
language = "English (US)",
volume = "121",
pages = "725--730",
journal = "Otolaryngology - Head and Neck Surgery (United States)",
issn = "0194-5998",
publisher = "Mosby Inc.",
number = "6",

}

TY - JOUR

T1 - Pharyngeal acid reflux in patients with single and multiple otolaryngologic disorders

AU - Ulualp, Seckin O.

AU - Toohill, Robert J.

AU - Shaker, Reza

PY - 1999

Y1 - 1999

N2 - OBJECTIVE: This study was designed to determine the prevalence and characteristics of pharyngeal acid reflux (PAR) events in single and multiple otolaryngologic disorders. METHODS: Sixty-seven patients with otolaryngologic symptoms and objective findings and 34 healthy control subjects were studied with an ambulatory 24-hour, 3-site pharyngoesophageal pH monitoring technique. Otolaryngologic diagnosis included isolated posterior laryngitis (PL) in 28 patients, isolated chronic rhinosinusitis (SIN) in 12, combined PL and SIN (PL+SIN) in 6, PL plus laryngotracheal stenosis (PL+LTS) in 12, and PL plus vocal cord nodules (PL+VCN) in 9. RESULTS: PAR events were documented in 68% of patients with PL, 34% of patients with SIN, 67% of patients with PL+SIN, 67% of patients with PL+LTS, 78% of patients with PL+VCN, and 21% of controls. The prevalence of PAR events in patients with isolated PL as well as those with PL combined with other disorders was significantly higher than that in patients without PL and that in controls. As a group, patients with PL had a greater number of PAR events and acid exposure time than other patients and controls. Distal and proximal esophageal reflux parameters were not significantly different among groups. CONCLUSIONS: The prevalence of PAR is significantly higher in patients with isolated PL compared to patients with other isolated otolaryngologic disorders and in controls. The prevalence of PAR in isolated otolaryngologlc disorders other than PL is similar to that in healthy controls. The prevalence of PAR is significantly higher in patients with both PL and other otolaryngologic disorders than in controls and in patients with isolated otolaryngologic disorders.

AB - OBJECTIVE: This study was designed to determine the prevalence and characteristics of pharyngeal acid reflux (PAR) events in single and multiple otolaryngologic disorders. METHODS: Sixty-seven patients with otolaryngologic symptoms and objective findings and 34 healthy control subjects were studied with an ambulatory 24-hour, 3-site pharyngoesophageal pH monitoring technique. Otolaryngologic diagnosis included isolated posterior laryngitis (PL) in 28 patients, isolated chronic rhinosinusitis (SIN) in 12, combined PL and SIN (PL+SIN) in 6, PL plus laryngotracheal stenosis (PL+LTS) in 12, and PL plus vocal cord nodules (PL+VCN) in 9. RESULTS: PAR events were documented in 68% of patients with PL, 34% of patients with SIN, 67% of patients with PL+SIN, 67% of patients with PL+LTS, 78% of patients with PL+VCN, and 21% of controls. The prevalence of PAR events in patients with isolated PL as well as those with PL combined with other disorders was significantly higher than that in patients without PL and that in controls. As a group, patients with PL had a greater number of PAR events and acid exposure time than other patients and controls. Distal and proximal esophageal reflux parameters were not significantly different among groups. CONCLUSIONS: The prevalence of PAR is significantly higher in patients with isolated PL compared to patients with other isolated otolaryngologic disorders and in controls. The prevalence of PAR in isolated otolaryngologlc disorders other than PL is similar to that in healthy controls. The prevalence of PAR is significantly higher in patients with both PL and other otolaryngologic disorders than in controls and in patients with isolated otolaryngologic disorders.

UR - http://www.scopus.com/inward/record.url?scp=0032763968&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032763968&partnerID=8YFLogxK

U2 - 10.1053/hn.1999.v121.a98010

DO - 10.1053/hn.1999.v121.a98010

M3 - Article

C2 - 10580227

AN - SCOPUS:0032763968

VL - 121

SP - 725

EP - 730

JO - Otolaryngology - Head and Neck Surgery (United States)

JF - Otolaryngology - Head and Neck Surgery (United States)

SN - 0194-5998

IS - 6

ER -