Phase separation of BuGZ promotes Aurora A activation and spindle assembly

Research output: Contribution to journalComment/debatepeer-review

1 Scopus citations

Abstract

The spindle matrix has been proposed to facilitate mitotic spindle assembly. In this issue, Huang et al. (2018. J. Cell Biol. https ://doi .org /10 .1083 /jcb .201706103) show that the spindle matrix protein BuGZ is sufficient to form micron-scale compartments that recruit and activate Aurora A, a critical kinase for spindle assembly.

Original languageEnglish (US)
Pages (from-to)9-10
Number of pages2
JournalJournal of Cell Biology
Volume217
Issue number1
DOIs
StatePublished - Jan 1 2018

ASJC Scopus subject areas

  • Cell Biology

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