Photodermatitis for the Allergist

Samuel L. Coffin, Jake E. Turrentine, Ponciano D Cruz

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Purpose of Review: The photodermatoses represent a group of disorders of sensitivity to light that continue to pose difficulties in diagnosis and management. Photodermatoses are of interest to allergists because many photosensitive skin disorders have immunologic underpinnings, and patients often present to clinic complaining of “allergy” to the sun. We provide a concise reference for allergists on the clinical recognition and management of photodermatitis. Recent Findings: New developments in the understanding of immunomodulatory effects of light have demonstrated normally immunosuppressive responses in the skin to light exposure, and a blunted immunosuppressive response in the pathogenesis of many photodermatoses. Vitamin D plays an important role in immunomodulation and itself may be affected by photodermatoses due to the impact of photoprotective treatment strategies on circulating vitamin D levels. Summary: The elucidation of the immunological basis of many photodermatoses may provide guidance for developing new treatment modalities. Further research is necessary to determine the optimal management of vitamin D metabolism in patients with photodermatoses.

Original languageEnglish (US)
Article number36
JournalCurrent Allergy and Asthma Reports
Volume17
Issue number6
DOIs
StatePublished - Jun 1 2017

Fingerprint

Photosensitivity Disorders
Vitamin D
Immunosuppressive Agents
Light
Photophobia
Skin
Immunomodulation
Solar System
Hypersensitivity
Therapeutics
Research
Allergists

Keywords

  • Photodermatitis
  • Photodermatoses
  • Photoimmunosuppression
  • Photoprotection
  • Regulatory T cell
  • Vitamin D

ASJC Scopus subject areas

  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine

Cite this

Photodermatitis for the Allergist. / Coffin, Samuel L.; Turrentine, Jake E.; Cruz, Ponciano D.

In: Current Allergy and Asthma Reports, Vol. 17, No. 6, 36, 01.06.2017.

Research output: Contribution to journalReview article

Coffin, Samuel L. ; Turrentine, Jake E. ; Cruz, Ponciano D. / Photodermatitis for the Allergist. In: Current Allergy and Asthma Reports. 2017 ; Vol. 17, No. 6.
@article{ade65e7b141f49e1a47f598fb3e80267,
title = "Photodermatitis for the Allergist",
abstract = "Purpose of Review: The photodermatoses represent a group of disorders of sensitivity to light that continue to pose difficulties in diagnosis and management. Photodermatoses are of interest to allergists because many photosensitive skin disorders have immunologic underpinnings, and patients often present to clinic complaining of “allergy” to the sun. We provide a concise reference for allergists on the clinical recognition and management of photodermatitis. Recent Findings: New developments in the understanding of immunomodulatory effects of light have demonstrated normally immunosuppressive responses in the skin to light exposure, and a blunted immunosuppressive response in the pathogenesis of many photodermatoses. Vitamin D plays an important role in immunomodulation and itself may be affected by photodermatoses due to the impact of photoprotective treatment strategies on circulating vitamin D levels. Summary: The elucidation of the immunological basis of many photodermatoses may provide guidance for developing new treatment modalities. Further research is necessary to determine the optimal management of vitamin D metabolism in patients with photodermatoses.",
keywords = "Photodermatitis, Photodermatoses, Photoimmunosuppression, Photoprotection, Regulatory T cell, Vitamin D",
author = "Coffin, {Samuel L.} and Turrentine, {Jake E.} and Cruz, {Ponciano D}",
year = "2017",
month = "6",
day = "1",
doi = "10.1007/s11882-017-0705-2",
language = "English (US)",
volume = "17",
journal = "Current Allergy and Asthma Reports",
issn = "1529-7322",
publisher = "Current Medicine Group",
number = "6",

}

TY - JOUR

T1 - Photodermatitis for the Allergist

AU - Coffin, Samuel L.

AU - Turrentine, Jake E.

AU - Cruz, Ponciano D

PY - 2017/6/1

Y1 - 2017/6/1

N2 - Purpose of Review: The photodermatoses represent a group of disorders of sensitivity to light that continue to pose difficulties in diagnosis and management. Photodermatoses are of interest to allergists because many photosensitive skin disorders have immunologic underpinnings, and patients often present to clinic complaining of “allergy” to the sun. We provide a concise reference for allergists on the clinical recognition and management of photodermatitis. Recent Findings: New developments in the understanding of immunomodulatory effects of light have demonstrated normally immunosuppressive responses in the skin to light exposure, and a blunted immunosuppressive response in the pathogenesis of many photodermatoses. Vitamin D plays an important role in immunomodulation and itself may be affected by photodermatoses due to the impact of photoprotective treatment strategies on circulating vitamin D levels. Summary: The elucidation of the immunological basis of many photodermatoses may provide guidance for developing new treatment modalities. Further research is necessary to determine the optimal management of vitamin D metabolism in patients with photodermatoses.

AB - Purpose of Review: The photodermatoses represent a group of disorders of sensitivity to light that continue to pose difficulties in diagnosis and management. Photodermatoses are of interest to allergists because many photosensitive skin disorders have immunologic underpinnings, and patients often present to clinic complaining of “allergy” to the sun. We provide a concise reference for allergists on the clinical recognition and management of photodermatitis. Recent Findings: New developments in the understanding of immunomodulatory effects of light have demonstrated normally immunosuppressive responses in the skin to light exposure, and a blunted immunosuppressive response in the pathogenesis of many photodermatoses. Vitamin D plays an important role in immunomodulation and itself may be affected by photodermatoses due to the impact of photoprotective treatment strategies on circulating vitamin D levels. Summary: The elucidation of the immunological basis of many photodermatoses may provide guidance for developing new treatment modalities. Further research is necessary to determine the optimal management of vitamin D metabolism in patients with photodermatoses.

KW - Photodermatitis

KW - Photodermatoses

KW - Photoimmunosuppression

KW - Photoprotection

KW - Regulatory T cell

KW - Vitamin D

UR - http://www.scopus.com/inward/record.url?scp=85018434978&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85018434978&partnerID=8YFLogxK

U2 - 10.1007/s11882-017-0705-2

DO - 10.1007/s11882-017-0705-2

M3 - Review article

C2 - 28477263

AN - SCOPUS:85018434978

VL - 17

JO - Current Allergy and Asthma Reports

JF - Current Allergy and Asthma Reports

SN - 1529-7322

IS - 6

M1 - 36

ER -