Photoimmunology is the study of the effects of ultraviolet (UV) light between the wavelengths of 100 and 400 nm, which encompasses UVC through UVA radiation on the immune system, particularly the skin immune system. Ultraviolet light can serve as a therapeutic modality to treat a number of dermatologic diseases. Ultraviolet exposure is a major environmental risk factor for nonmelanoma skin cancer because of its mutagenic effects on epidermal cells, as well as its ability to suppress cutaneous immunosurveillance. Ultraviolet light is responsible for inducing or exacerbating a number of dermatologic diseases, termed photosensitivity disorders.
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