Photoimmunology-illuminating the immune system through photobiology

Justin Leitenberger, Heidi Jacobe, Ponciano D Cruz

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

We review the field of photoimmunology with emphasis on immunosuppression induced by ultraviolet B radiation. Recent studies have focused on UVB-induced alterations in epidermal Langerhans cell function, resulting in a shift from Th1 to Th2 phenotype and the activation of regulatory T cells as the source of IL-10 that is central to this form of immunosuppression.

Original languageEnglish (US)
Pages (from-to)65-70
Number of pages6
JournalSeminars in Immunopathology
Volume29
Issue number1
DOIs
StatePublished - Apr 2007

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Photobiology
Immunosuppression
Immune System
Langerhans Cells
Regulatory T-Lymphocytes
Interleukin-10
Radiation
Phenotype

Keywords

  • Antigen-presenting cells
  • Cytokines
  • Immunosuppression
  • Regulatory T cells
  • Ultraviolet radiation

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

Cite this

Photoimmunology-illuminating the immune system through photobiology. / Leitenberger, Justin; Jacobe, Heidi; Cruz, Ponciano D.

In: Seminars in Immunopathology, Vol. 29, No. 1, 04.2007, p. 65-70.

Research output: Contribution to journalArticle

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