Phototherapy and HIV infection

Hallie McDonald, Ponciano D Cruz

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

In vitro studies indicate UV radiation activates HIV gene expression. To repair DNA damage caused by UV, cells turn on genes, including HIV genes; however, the overall effect of increased viral load in skin may be insignificant. UV may produce adverse effects by inhibiting TH1 protective immune responses and promoting TH2 tolerogenic immune responses. Phototherapy improves psoriasis, eosinophilic folliculitis, atopic dermatitis, and pruritus in HIV-infected individuals. There is no compelling proof that UVB or PUVA treatment leads to harmful systemic effects in HIV-infected patients.

Original languageEnglish (US)
Title of host publicationDermatological Phototherapy and Photodiagnostic Methods
PublisherSpringer Berlin Heidelberg
Pages229-237
Number of pages9
ISBN (Print)9783540366928
DOIs
StatePublished - 2009

Fingerprint

Phototherapy
HIV Infections
HIV
Folliculitis
Atopic Dermatitis
Pruritus
Viral Load
Psoriasis
Genes
DNA Damage
Radiation
Gene Expression
Skin
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

McDonald, H., & Cruz, P. D. (2009). Phototherapy and HIV infection. In Dermatological Phototherapy and Photodiagnostic Methods (pp. 229-237). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-540-36693-5_10

Phototherapy and HIV infection. / McDonald, Hallie; Cruz, Ponciano D.

Dermatological Phototherapy and Photodiagnostic Methods. Springer Berlin Heidelberg, 2009. p. 229-237.

Research output: Chapter in Book/Report/Conference proceedingChapter

McDonald, H & Cruz, PD 2009, Phototherapy and HIV infection. in Dermatological Phototherapy and Photodiagnostic Methods. Springer Berlin Heidelberg, pp. 229-237. https://doi.org/10.1007/978-3-540-36693-5_10
McDonald H, Cruz PD. Phototherapy and HIV infection. In Dermatological Phototherapy and Photodiagnostic Methods. Springer Berlin Heidelberg. 2009. p. 229-237 https://doi.org/10.1007/978-3-540-36693-5_10
McDonald, Hallie ; Cruz, Ponciano D. / Phototherapy and HIV infection. Dermatological Phototherapy and Photodiagnostic Methods. Springer Berlin Heidelberg, 2009. pp. 229-237
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