Physiologic measurement of exercise and fatigue with special reference to chronic fatigue syndrome

S. F. Lewis, R. G. Haller

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Oxidative metabolism is the major source of energy for muscle activity, and maximal oxygen uptake (V̇O(2max)), the product of maximal cardiac output and maximal arteriovenous oxygen difference, indicates individual capacity for oxidative metabolism and performance of exercise by the large muscles. Strength, a function of muscle cross-sectional area, motor-unit recruitment, and neuromuscular coordination, is the ability to develop force in a single, brief, maximal-effort voluntary contraction of rested muscle. Weakness is a diminished ability of rested muscle to exert maximal force. Fatigue is a loss of maximal force-generating capacity that develops during muscular activity, likely originates within muscle itself, and persists until muscle is fully recovered. Individual perception of motor effort can be determined with standardized rating scales. These concepts are discussed in detail, their relevance to the pathophysiology of exercise in chronic fatigue syndrome is analyzed, and a general strategy of exercise evaluation pertinent to chronic fatigue syndrome is presented.

Original languageEnglish (US)
JournalReviews of Infectious Diseases
Volume13
Issue numberSUPPL. 1
StatePublished - 1991

Fingerprint

Chronic Fatigue Syndrome
Fatigue
Muscles
Aptitude
Neurophysiological Recruitment
Oxygen
Muscle Contraction
Individuality
Cardiac Output

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Physiologic measurement of exercise and fatigue with special reference to chronic fatigue syndrome. / Lewis, S. F.; Haller, R. G.

In: Reviews of Infectious Diseases, Vol. 13, No. SUPPL. 1, 1991.

Research output: Contribution to journalArticle

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