Piezo-electric coupling of membrane proteins

Tian Y. Tsong, Vladislav S. Markin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A membrane protein responds to pressure perturbation if the molar volume of its various conformational states has different values, or if these states have different contact areas with the lipid bilayer. An oscillating pressure can then drive the protein to oscillate among its various conformational states within the catalytic cycle. It is shown that this property of an ion transporter enables it to absorb energy from the pressure wave to actively pump an ion against its concentration gradient, thus converting the pressure energy into the electrochemical potential energy of an ion, and vice versa. An electroformational coupling model developed earlier is applied to formulate an efficient piezoelectric transducer. With reasonable assumptions on the cell membrane parameters, the model can easily generate a membrane potential on the order of 100 mV.

Original languageEnglish (US)
Title of host publicationProceedings of the Annual Conference on Engineering in Medicine and Biology
Place of PublicationPiscataway, NJ, United States
PublisherPubl by IEEE
Pages1763
Number of pages1
Editionpt 4
ISBN (Print)0879425598
StatePublished - 1990
EventProceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Philadelphia, PA, USA
Duration: Nov 1 1990Nov 4 1990

Other

OtherProceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityPhiladelphia, PA, USA
Period11/1/9011/4/90

Fingerprint

Membrane Proteins
Proteins
Membranes
Ions
Ion Pumps
Lipid bilayers
Piezoelectric transducers
Cell membranes
Potential energy
Density (specific gravity)
Pumps

ASJC Scopus subject areas

  • Bioengineering

Cite this

Tsong, T. Y., & Markin, V. S. (1990). Piezo-electric coupling of membrane proteins. In Proceedings of the Annual Conference on Engineering in Medicine and Biology (pt 4 ed., pp. 1763). Piscataway, NJ, United States: Publ by IEEE.

Piezo-electric coupling of membrane proteins. / Tsong, Tian Y.; Markin, Vladislav S.

Proceedings of the Annual Conference on Engineering in Medicine and Biology. pt 4. ed. Piscataway, NJ, United States : Publ by IEEE, 1990. p. 1763.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tsong, TY & Markin, VS 1990, Piezo-electric coupling of membrane proteins. in Proceedings of the Annual Conference on Engineering in Medicine and Biology. pt 4 edn, Publ by IEEE, Piscataway, NJ, United States, pp. 1763, Proceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Philadelphia, PA, USA, 11/1/90.
Tsong TY, Markin VS. Piezo-electric coupling of membrane proteins. In Proceedings of the Annual Conference on Engineering in Medicine and Biology. pt 4 ed. Piscataway, NJ, United States: Publ by IEEE. 1990. p. 1763
Tsong, Tian Y. ; Markin, Vladislav S. / Piezo-electric coupling of membrane proteins. Proceedings of the Annual Conference on Engineering in Medicine and Biology. pt 4. ed. Piscataway, NJ, United States : Publ by IEEE, 1990. pp. 1763
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