Pigmented epithelial cells of the membranous saccular wall of the Chinchilla

Charles G. Wright, D. H. Lee

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Wright CG, Lee DH. Pigmented epithelial cells of the membranous saccular wall of the chinchilla. Acta Otolaryngol (Stockh) 1986; 102:438-449. The Posterior-superior portion of the membranous wall of the chinchilla saccule is lined by pigmented epithelial cells which contain golden brown granules having three components (lipid droplets, granular matrix, and dense globules). Histochemical and electronmicroscopic studies indicate that the dense component is a form of melanin. The pigmented cells show morphological features suggestive of fluid transport function; they are also involved in decal-cification and phagocytosis of otoconial crystals. These findings provide evidence that the saccular wall epithelium plays an active role in regulating endolymph composition and in clearance of debris from the endolymphatic space.

Original languageEnglish (US)
Pages (from-to)438-449
Number of pages12
JournalActa Oto-Laryngologica
Volume102
Issue number5-6
DOIs
StatePublished - Jan 1 1986

Keywords

  • Fluid transport
  • Melanin
  • Otoconia
  • Phagocytosis
  • Saccule
  • Vestibular apparatus

ASJC Scopus subject areas

  • Otorhinolaryngology

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