Piperacillin and a combination of clindamycin and gentamicin for the treatment of hospital and community acquired acute pelvic infections including pelvic abscess

D. L. Hemsell, P. G. Hemsell, M. C. Heard, B. J. Nobles

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Therapy for acute polymicrobial pelvic infections is empiric and must include predictable anaerobic coverage. Single agent therapy, if effective, is advantageous for the patient, nurses, pharmacy and hospital. Piperacillin sodium was compared with a combination of clindamycin and gentamicin as therapy for 63 female patients who were hospitalized with acute pelvic infections including pelvic abscess complicating community acquired salpingitis. Over-all clinical efficacy with piperacillin was 96.8 per cent and 90.3 per cent for clindamycin and gentamicin. Fewer bacteria demonstrated in vitro resistance to piperacillin (p = 0.008) and the cost of treatment for these infections was significantly less with piperacillin (p < 0.05). Serious adverse reactions were not observed with either regimen. Piperacillin provides effective, cost-efficient therapy for women with acute polymicrobial pelvic infections.

Original languageEnglish (US)
Pages (from-to)223-229
Number of pages7
JournalSurgery Gynecology and Obstetrics
Volume165
Issue number3
StatePublished - 1987

Fingerprint

Pelvic Infection
Piperacillin
Clindamycin
Gentamicins
Abscess
Coinfection
Salpingitis
Therapeutics
Health Care Costs
Nurses
Bacteria
Costs and Cost Analysis
Infection

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Surgery

Cite this

Piperacillin and a combination of clindamycin and gentamicin for the treatment of hospital and community acquired acute pelvic infections including pelvic abscess. / Hemsell, D. L.; Hemsell, P. G.; Heard, M. C.; Nobles, B. J.

In: Surgery Gynecology and Obstetrics, Vol. 165, No. 3, 1987, p. 223-229.

Research output: Contribution to journalArticle

@article{5d3cff9fca2a4863bd2b580982c384b3,
title = "Piperacillin and a combination of clindamycin and gentamicin for the treatment of hospital and community acquired acute pelvic infections including pelvic abscess",
abstract = "Therapy for acute polymicrobial pelvic infections is empiric and must include predictable anaerobic coverage. Single agent therapy, if effective, is advantageous for the patient, nurses, pharmacy and hospital. Piperacillin sodium was compared with a combination of clindamycin and gentamicin as therapy for 63 female patients who were hospitalized with acute pelvic infections including pelvic abscess complicating community acquired salpingitis. Over-all clinical efficacy with piperacillin was 96.8 per cent and 90.3 per cent for clindamycin and gentamicin. Fewer bacteria demonstrated in vitro resistance to piperacillin (p = 0.008) and the cost of treatment for these infections was significantly less with piperacillin (p < 0.05). Serious adverse reactions were not observed with either regimen. Piperacillin provides effective, cost-efficient therapy for women with acute polymicrobial pelvic infections.",
author = "Hemsell, {D. L.} and Hemsell, {P. G.} and Heard, {M. C.} and Nobles, {B. J.}",
year = "1987",
language = "English (US)",
volume = "165",
pages = "223--229",
journal = "Journal of the American College of Surgeons",
issn = "1072-7515",
publisher = "Elsevier Inc.",
number = "3",

}

TY - JOUR

T1 - Piperacillin and a combination of clindamycin and gentamicin for the treatment of hospital and community acquired acute pelvic infections including pelvic abscess

AU - Hemsell, D. L.

AU - Hemsell, P. G.

AU - Heard, M. C.

AU - Nobles, B. J.

PY - 1987

Y1 - 1987

N2 - Therapy for acute polymicrobial pelvic infections is empiric and must include predictable anaerobic coverage. Single agent therapy, if effective, is advantageous for the patient, nurses, pharmacy and hospital. Piperacillin sodium was compared with a combination of clindamycin and gentamicin as therapy for 63 female patients who were hospitalized with acute pelvic infections including pelvic abscess complicating community acquired salpingitis. Over-all clinical efficacy with piperacillin was 96.8 per cent and 90.3 per cent for clindamycin and gentamicin. Fewer bacteria demonstrated in vitro resistance to piperacillin (p = 0.008) and the cost of treatment for these infections was significantly less with piperacillin (p < 0.05). Serious adverse reactions were not observed with either regimen. Piperacillin provides effective, cost-efficient therapy for women with acute polymicrobial pelvic infections.

AB - Therapy for acute polymicrobial pelvic infections is empiric and must include predictable anaerobic coverage. Single agent therapy, if effective, is advantageous for the patient, nurses, pharmacy and hospital. Piperacillin sodium was compared with a combination of clindamycin and gentamicin as therapy for 63 female patients who were hospitalized with acute pelvic infections including pelvic abscess complicating community acquired salpingitis. Over-all clinical efficacy with piperacillin was 96.8 per cent and 90.3 per cent for clindamycin and gentamicin. Fewer bacteria demonstrated in vitro resistance to piperacillin (p = 0.008) and the cost of treatment for these infections was significantly less with piperacillin (p < 0.05). Serious adverse reactions were not observed with either regimen. Piperacillin provides effective, cost-efficient therapy for women with acute polymicrobial pelvic infections.

UR - http://www.scopus.com/inward/record.url?scp=0023636479&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023636479&partnerID=8YFLogxK

M3 - Article

C2 - 3306994

AN - SCOPUS:0023636479

VL - 165

SP - 223

EP - 229

JO - Journal of the American College of Surgeons

JF - Journal of the American College of Surgeons

SN - 1072-7515

IS - 3

ER -