Plasma 24S hydroxycholesterol response to statins in Alzheimer's disease patients: Effects of gender, CYP46, and ApoE polymorphisms

Medicine & Life Sciences

• Cytochrome P450 Family 46 100%
• 24-hydroxycholesterol 84%
• Apolipoproteins E 52%
• Hydroxymethylglutaryl-CoA Reductase Inhibitors 47%
• Alzheimer Disease 38%
• Cholesterol 36%
• Oxysterols 26%
• Brain 9%
• Lovastatin 8%
• Pravastatin 8%
• Vascular Dementia 7%
• Simvastatin 7%
• Blood-Brain Barrier 5%
• Lipoproteins 5%
• Duration of Therapy 5%
• Epidemiologic Studies 5%
• Central Nervous System 4%
• Cell Membrane 4%
• Liver 3%
• Incidence 2%
• Pharmaceutical Preparations 2%
• Therapeutics 2%