Plasma catecholamine concentrations of newborn piglets in thermoneutral and cold environments

S. R. Mayfield, B. S. Stonestreet, P. W. Shaul, A. M. Brubakk, J. Susa, W. Oh

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Plasma epinephrine and norepinephrine concentrations were measured in seventeen unanaesthetized 3 to 4 days-old piglets while in a thermoneutral environment (31.3°C) and 30, 45 and 60 min after induction of environmental cold stress (19.9-23.1°C). Plasma epinephrine and norepinephrine concentrations in a warm environment were 142 ± 26 pg/ml, and 456 ± 44 pg/ml respectively. Environmental cold stress evoked significant increases in norepinephrine values after 30 (624 ± 58 pg/ml), 45 (626 ± 60 pg/ml) and 60 (626 ± 54 pg/ml) min of cold stress. Plasma epinephrine concentrations did not significantly change during environmental cold stress. Post-hoc stratification of piglets into normothermic (deep rectal temperature 38.6°C-38.8°C, n = 9) and hypothermic (deep rectal temperature 37.1°C-37.7°C, n = 7) subgroups revealed significant increases in plasma norepinephrine concentrations only in the hypothermic subgroup. We conclude that plasma norepinephrine, but not epinephrine, is increased in newborn piglets during environmental cold stress and that the changes in norepinephrine concentrations are related to body core hypothermia. We speculate that hypothermia-mediated reductions in peripheral norepinephrine breakdown and re-uptake contribute to the rise in circulating levels.

Original languageEnglish (US)
Pages (from-to)331-334
Number of pages4
JournalJournal of Developmental Physiology
Volume11
Issue number6
StatePublished - 1989

Fingerprint

Catecholamines
Norepinephrine
Epinephrine
Hypothermia
Temperature

ASJC Scopus subject areas

  • Developmental Biology
  • Physiology

Cite this

Mayfield, S. R., Stonestreet, B. S., Shaul, P. W., Brubakk, A. M., Susa, J., & Oh, W. (1989). Plasma catecholamine concentrations of newborn piglets in thermoneutral and cold environments. Journal of Developmental Physiology, 11(6), 331-334.

Plasma catecholamine concentrations of newborn piglets in thermoneutral and cold environments. / Mayfield, S. R.; Stonestreet, B. S.; Shaul, P. W.; Brubakk, A. M.; Susa, J.; Oh, W.

In: Journal of Developmental Physiology, Vol. 11, No. 6, 1989, p. 331-334.

Research output: Contribution to journalArticle

Mayfield, SR, Stonestreet, BS, Shaul, PW, Brubakk, AM, Susa, J & Oh, W 1989, 'Plasma catecholamine concentrations of newborn piglets in thermoneutral and cold environments', Journal of Developmental Physiology, vol. 11, no. 6, pp. 331-334.
Mayfield, S. R. ; Stonestreet, B. S. ; Shaul, P. W. ; Brubakk, A. M. ; Susa, J. ; Oh, W. / Plasma catecholamine concentrations of newborn piglets in thermoneutral and cold environments. In: Journal of Developmental Physiology. 1989 ; Vol. 11, No. 6. pp. 331-334.
@article{196461e7a6be46f2a2d5d8730d9a6b44,
title = "Plasma catecholamine concentrations of newborn piglets in thermoneutral and cold environments",
abstract = "Plasma epinephrine and norepinephrine concentrations were measured in seventeen unanaesthetized 3 to 4 days-old piglets while in a thermoneutral environment (31.3°C) and 30, 45 and 60 min after induction of environmental cold stress (19.9-23.1°C). Plasma epinephrine and norepinephrine concentrations in a warm environment were 142 ± 26 pg/ml, and 456 ± 44 pg/ml respectively. Environmental cold stress evoked significant increases in norepinephrine values after 30 (624 ± 58 pg/ml), 45 (626 ± 60 pg/ml) and 60 (626 ± 54 pg/ml) min of cold stress. Plasma epinephrine concentrations did not significantly change during environmental cold stress. Post-hoc stratification of piglets into normothermic (deep rectal temperature 38.6°C-38.8°C, n = 9) and hypothermic (deep rectal temperature 37.1°C-37.7°C, n = 7) subgroups revealed significant increases in plasma norepinephrine concentrations only in the hypothermic subgroup. We conclude that plasma norepinephrine, but not epinephrine, is increased in newborn piglets during environmental cold stress and that the changes in norepinephrine concentrations are related to body core hypothermia. We speculate that hypothermia-mediated reductions in peripheral norepinephrine breakdown and re-uptake contribute to the rise in circulating levels.",
author = "Mayfield, {S. R.} and Stonestreet, {B. S.} and Shaul, {P. W.} and Brubakk, {A. M.} and J. Susa and W. Oh",
year = "1989",
language = "English (US)",
volume = "11",
pages = "331--334",
journal = "Journal of Developmental Physiology",
issn = "0141-9846",
number = "6",

}

TY - JOUR

T1 - Plasma catecholamine concentrations of newborn piglets in thermoneutral and cold environments

AU - Mayfield, S. R.

AU - Stonestreet, B. S.

AU - Shaul, P. W.

AU - Brubakk, A. M.

AU - Susa, J.

AU - Oh, W.

PY - 1989

Y1 - 1989

N2 - Plasma epinephrine and norepinephrine concentrations were measured in seventeen unanaesthetized 3 to 4 days-old piglets while in a thermoneutral environment (31.3°C) and 30, 45 and 60 min after induction of environmental cold stress (19.9-23.1°C). Plasma epinephrine and norepinephrine concentrations in a warm environment were 142 ± 26 pg/ml, and 456 ± 44 pg/ml respectively. Environmental cold stress evoked significant increases in norepinephrine values after 30 (624 ± 58 pg/ml), 45 (626 ± 60 pg/ml) and 60 (626 ± 54 pg/ml) min of cold stress. Plasma epinephrine concentrations did not significantly change during environmental cold stress. Post-hoc stratification of piglets into normothermic (deep rectal temperature 38.6°C-38.8°C, n = 9) and hypothermic (deep rectal temperature 37.1°C-37.7°C, n = 7) subgroups revealed significant increases in plasma norepinephrine concentrations only in the hypothermic subgroup. We conclude that plasma norepinephrine, but not epinephrine, is increased in newborn piglets during environmental cold stress and that the changes in norepinephrine concentrations are related to body core hypothermia. We speculate that hypothermia-mediated reductions in peripheral norepinephrine breakdown and re-uptake contribute to the rise in circulating levels.

AB - Plasma epinephrine and norepinephrine concentrations were measured in seventeen unanaesthetized 3 to 4 days-old piglets while in a thermoneutral environment (31.3°C) and 30, 45 and 60 min after induction of environmental cold stress (19.9-23.1°C). Plasma epinephrine and norepinephrine concentrations in a warm environment were 142 ± 26 pg/ml, and 456 ± 44 pg/ml respectively. Environmental cold stress evoked significant increases in norepinephrine values after 30 (624 ± 58 pg/ml), 45 (626 ± 60 pg/ml) and 60 (626 ± 54 pg/ml) min of cold stress. Plasma epinephrine concentrations did not significantly change during environmental cold stress. Post-hoc stratification of piglets into normothermic (deep rectal temperature 38.6°C-38.8°C, n = 9) and hypothermic (deep rectal temperature 37.1°C-37.7°C, n = 7) subgroups revealed significant increases in plasma norepinephrine concentrations only in the hypothermic subgroup. We conclude that plasma norepinephrine, but not epinephrine, is increased in newborn piglets during environmental cold stress and that the changes in norepinephrine concentrations are related to body core hypothermia. We speculate that hypothermia-mediated reductions in peripheral norepinephrine breakdown and re-uptake contribute to the rise in circulating levels.

UR - http://www.scopus.com/inward/record.url?scp=0024341909&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024341909&partnerID=8YFLogxK

M3 - Article

VL - 11

SP - 331

EP - 334

JO - Journal of Developmental Physiology

JF - Journal of Developmental Physiology

SN - 0141-9846

IS - 6

ER -