Abstract
In eleven dogs made hypotensive by means of rapid exsanguination over a period of 40 to 70 min, mean glucagon rose to a peak of 516 ± (S.E.) 150 pg/ml and mean glucose to a peak of 341 ± 27 mg per 100 ml. The hyperglucagonemia induced by exsanguination was substantially reduced, although not abolished, by propranolol infusion, but was not diminished by phentolamine, suggesting that it was largely a β adrenergic effect. Its possible contribution to survival during shock is considered.
Original language | English (US) |
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Pages (from-to) | 313-316 |
Number of pages | 4 |
Journal | Diabetes |
Volume | 24 |
Issue number | 4 |
State | Published - Dec 1 1975 |
ASJC Scopus subject areas
- Internal Medicine
- Endocrinology, Diabetes and Metabolism