Plasma ropivacaine levels during awake intracranial surgery

Paul B. Audu, Chuck Wilkerson, Richard Bartkowski, Kevin Gingrich, Eugene Viscusi, David Andrews

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Plasma ropivacaine levels produced by routine scalp infiltration for field block were assayed in eight patients undergoing awake intracranial surgery. Levels peaked within approximately 13 minutes, indicating rapid systemic absorption of ropivacaine. Potentially toxic plasma drug levels were achieved in three of eight patients, although no untoward effects attributable to elevated levels of ropivacaine were observed. Clinical vigilance is indicated during scalp infiltration with ropivacaine.

Original languageEnglish (US)
Pages (from-to)153-155
Number of pages3
JournalJournal of Neurosurgical Anesthesiology
Volume17
Issue number3
DOIs
StatePublished - Jul 2005

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Scalp
Poisons
ropivacaine
Pharmaceutical Preparations
Physiological Absorption

Keywords

  • Awake craniotomy
  • Local anesthetic toxicity
  • Ropivacaine

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Clinical Neurology

Cite this

Plasma ropivacaine levels during awake intracranial surgery. / Audu, Paul B.; Wilkerson, Chuck; Bartkowski, Richard; Gingrich, Kevin; Viscusi, Eugene; Andrews, David.

In: Journal of Neurosurgical Anesthesiology, Vol. 17, No. 3, 07.2005, p. 153-155.

Research output: Contribution to journalArticle

Audu, Paul B. ; Wilkerson, Chuck ; Bartkowski, Richard ; Gingrich, Kevin ; Viscusi, Eugene ; Andrews, David. / Plasma ropivacaine levels during awake intracranial surgery. In: Journal of Neurosurgical Anesthesiology. 2005 ; Vol. 17, No. 3. pp. 153-155.
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