Platinum-catalyzed synthesis of β-keto tetrahydropyrans and cyclic dienolethers

Qiren Liang, Mingxing Qian, Mina Razzak, Jef K. De Brabander

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

A platinum upgrade: Zeise's dimer [{Cl2Pt(CH2CH 2)}2] catalyzes the activation of linear propargylic alcohols and esters. Depending on the presence of a suitably placed alcohol group proximal or distal to the propargylic center, a cyclo-reorganization occurs that delivers either valuable β-keto tetrahydropyrans (from propargylic alcohols), or cyclic dienolethers (from propargylic esters).

Original languageEnglish (US)
Pages (from-to)1958-1960
Number of pages3
JournalChemistry - An Asian Journal
Volume6
Issue number8
DOIs
StatePublished - Aug 1 2011

Keywords

  • cycloisomerization
  • dienolethers
  • platinum
  • tetrahydropyrans
  • transition metal catalysis

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry

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