Pleural fluid extramedullary hematopoiesis case report with review of the literature

Meghan Koch, Elizabeth M. Kurian

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Extramedullary hematopoiesis (EMH) is the trilineage formation of normal blood cells outside of the bone marrow. While predominantly seen in the spleen and liver, EMH rarely occurs in serous effusions. Accurate diagnosis requires recognition of megakaryocytes and other precursor hematopoietic elements. We present a case of pleural fluid EMH in a patient with primary myelofibrosis and developing leukemia, with a review of the literature, prognostic implications and diagnostic challenges.

Original languageEnglish (US)
Pages (from-to)41-44
Number of pages4
JournalDiagnostic Cytopathology
Volume44
Issue number1
DOIs
StatePublished - Jan 1 2016

Keywords

  • effusion
  • EMH
  • extramedullary hematopoiesis
  • megakaryocyte
  • pleural fluid

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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