Pneumococcal Neuraminidase Substrates Identified through Comparative Proteomics Enabled by Chemoselective Labeling

Engineering & Materials Science

• Glycoproteins 100%
• Proteomics 78%
• Labeling 56%
• Pathogens 45%
• Substrates 41%
• Oximes 31%
• Aniline 25%
• Bacteria 18%
• Glycoconjugates 17%
• Protozoa 15%
• Blood-Brain Barrier 14%
• Oxidoreductases 12%
• Fungi 11%
• Cell membranes 11%
• Lipids 11%
• Viruses 9%
• Assays 9%
• Enzymes 9%
• Molecules 8%
• Cells 8%
• Proteins 7%
• Acids 7%
• Oxidation 7%

Medicine & Life Sciences

• Neuraminidase 66%
• Proteomics 53%
• Glycoproteins 22%
• aniline 18%
• Oximes 18%
• Membrane Glycoproteins 14%
• Ligation 11%
• Asialoglycoproteins 11%
• Galactose Oxidase 10%
• metaperiodate 9%
• Bacteria 8%
• Glycoconjugates 8%
• N-Acetylneuraminic Acid 7%
• Virulence Factors 6%
• Streptococcus pneumoniae 6%
• Blood-Brain Barrier 6%
• Infections 6%
• Fungi 5%
• Cell Membrane 4%
• Viruses 4%
• Lipids 4%
• Cell Line 3%
• Enzymes 3%
• Proteins 2%

Chemical Compounds

• Chemoselectivity 57%
• Glycoprotein 53%
• Oxime 16%
• Virulence Factor 11%
• Periodate 9%
• Sialic Acid 9%
• Galactose 8%
• Lipid 5%
• Surface 5%
• Plasma 5%
• Oxidation Reaction 3%
• Protein 3%
• Molecule 2%