Pneumococcal otitis media following middle ear deflation

W. L. Meyerhoff, G. S. Giebink, D. Shea

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Temporal bone histology has been studied in chinchillas following middle ear deflation in the presence of nasopharyngeal colonization with S pneumoniae. All animals sacrificed within one hour following deflation had similar middle ear histology regardless of whether or not the animals had been colonized with S pneumoniae. All animals with negative nasopharyngeal culture for S pneumoniae sacrificed from 3-24 days following -30 mm Hg negative middle ear pressure had negative middle ear cultures and normal morphology. During the same time period, however, nearly 60% of animals colonized with S pneumoniae developed acute otitis media with positive middle ear cultures for S pneumoniae. Histologic changes in the middle ear included the presence of effusion, leukocytes, granulation tissue, osteoneogenesis, mucosal metaplasia, and hemorrhage. Changes in the inner ear were much less frequent and included some leukocyte infiltration with hyperemia in the scala tympani and endolymphatic hydrops.

Original languageEnglish (US)
Pages (from-to)72-76
Number of pages5
JournalAnnals of Otology, Rhinology and Laryngology
Volume90
Issue number1 I
StatePublished - 1981

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Otitis Media
Middle Ear
Pneumonia
Histology
Leukocytes
Scala Tympani
Endolymphatic Hydrops
Chinchilla
Granulation Tissue
Temporal Bone
Hyperemia
Metaplasia
Inner Ear
Hemorrhage
Pressure

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Meyerhoff, W. L., Giebink, G. S., & Shea, D. (1981). Pneumococcal otitis media following middle ear deflation. Annals of Otology, Rhinology and Laryngology, 90(1 I), 72-76.

Pneumococcal otitis media following middle ear deflation. / Meyerhoff, W. L.; Giebink, G. S.; Shea, D.

In: Annals of Otology, Rhinology and Laryngology, Vol. 90, No. 1 I, 1981, p. 72-76.

Research output: Contribution to journalArticle

Meyerhoff, WL, Giebink, GS & Shea, D 1981, 'Pneumococcal otitis media following middle ear deflation', Annals of Otology, Rhinology and Laryngology, vol. 90, no. 1 I, pp. 72-76.
Meyerhoff, W. L. ; Giebink, G. S. ; Shea, D. / Pneumococcal otitis media following middle ear deflation. In: Annals of Otology, Rhinology and Laryngology. 1981 ; Vol. 90, No. 1 I. pp. 72-76.
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