Poising chromatin for transcription

David S. Gross, William T. Garrard

Research output: Contribution to journalArticle

82 Citations (Scopus)

Abstract

Interactions between cis-acting DNA sequences and trans-acting factors regulate gene expression in eukaryotic cells. In chromatin, these protein-DNA complexes frequently generate DNase I hypersensitive sites, are sometimes organized at or near the bases of chromosomal loops, and can instruct an entire linked domain to memorize the transcriptionally poised state.

Original languageEnglish (US)
Pages (from-to)293-297
Number of pages5
JournalTrends in Biochemical Sciences
Volume12
Issue numberC
DOIs
StatePublished - 1987

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Trans-Activators
Deoxyribonuclease I
DNA sequences
Eukaryotic Cells
Transcription
Gene expression
Chromatin
Gene Expression
DNA
Proteins

ASJC Scopus subject areas

  • Biochemistry

Cite this

Poising chromatin for transcription. / Gross, David S.; Garrard, William T.

In: Trends in Biochemical Sciences, Vol. 12, No. C, 1987, p. 293-297.

Research output: Contribution to journalArticle

Gross, David S. ; Garrard, William T. / Poising chromatin for transcription. In: Trends in Biochemical Sciences. 1987 ; Vol. 12, No. C. pp. 293-297.
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