Polyarteritis in children

E. W. Reimold, A. G. Weinberg, C. W. Fink, N. D. Battles

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Polyarteritis, the cause of which is still unclear, is characterized by focal necrosis of the walls of small and medium sized arteries. It is a rare disease in children. The disease was diagnosed in 3 girls, 9 to 10 yr old, by kidney and skin biopsies. They were treated with a combination of prednisone (1.5 to 2 mg/kg) and cyclophosphamide (2 mg/kg) for up to 12 mth. The illness was severe in all three, complicated by hypertension, seizures, pulmonary infiltrates, renal failure, or hallucination. All three patients are alive and well with no or minimal residual symptoms two to three years after therapy was discontinued. The treatment with corticosteroids or with a combination of steroids and immunosuppressive drugs seems to improve the prognosis of polyarteritis considerably.

Original languageEnglish (US)
Pages (from-to)534-541
Number of pages8
JournalAmerican Journal of Diseases of Children
Volume130
Issue number5
StatePublished - 1976

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Hallucinations
Immunosuppressive Agents
Rare Diseases
Prednisone
Pulmonary Hypertension
Cyclophosphamide
Renal Insufficiency
Adrenal Cortex Hormones
Seizures
Necrosis
Arteries
Steroids
Kidney
Biopsy
Skin
Therapeutics
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Reimold, E. W., Weinberg, A. G., Fink, C. W., & Battles, N. D. (1976). Polyarteritis in children. American Journal of Diseases of Children, 130(5), 534-541.

Polyarteritis in children. / Reimold, E. W.; Weinberg, A. G.; Fink, C. W.; Battles, N. D.

In: American Journal of Diseases of Children, Vol. 130, No. 5, 1976, p. 534-541.

Research output: Contribution to journalArticle

Reimold, EW, Weinberg, AG, Fink, CW & Battles, ND 1976, 'Polyarteritis in children', American Journal of Diseases of Children, vol. 130, no. 5, pp. 534-541.
Reimold EW, Weinberg AG, Fink CW, Battles ND. Polyarteritis in children. American Journal of Diseases of Children. 1976;130(5):534-541.
Reimold, E. W. ; Weinberg, A. G. ; Fink, C. W. ; Battles, N. D. / Polyarteritis in children. In: American Journal of Diseases of Children. 1976 ; Vol. 130, No. 5. pp. 534-541.
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