Polyarteritis in Children

E. W. Reimold, A. G. Weinberg, C. W. Fink, N. D. Battles

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Abstract

Polyarteritis was diagnosed in three girls, 9 to 10 years old, by kidney and skin biopsies. They were treated with a combination of prednisone (1.5 to 2 mg/kg) and cyclophosphamide (2 mg/kg) for up to 12 months. The illness was severe in all three, complicated by hypertension, seizures, pulmonary infiltrates, renal failure, or hallucinations. All three patients are alive and well with no or minimal residual symptoms two to three years after therapy was discontinued. The treatment with corticosteroids or with a combination of steroids and immunosuppressive drugs seems to improve the prognosis of polyarteritis considerably.

Original languageEnglish (US)
Pages (from-to)534-541
Number of pages8
JournalAmerican Journal of Diseases of Children
Volume130
Issue number5
DOIs
StatePublished - May 1976

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ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Reimold, E. W., Weinberg, A. G., Fink, C. W., & Battles, N. D. (1976). Polyarteritis in Children. American Journal of Diseases of Children, 130(5), 534-541. https://doi.org/10.1001/archpedi.1976.02120060080015