Poly(L-lysine)-graft-dextran copolymer promotes pyrimidine motif triplex DNA formation at physiological pH. Thermodynamic and kinetic studies

Medicine & Life Sciences

• poly(lysine)-graft-dextran 100%
• triplex DNA 64%
• pyrimidine 47%
• Thermodynamics 47%
• Kinetics 28%
• Synthetic Genes 9%
• Calorimetry 8%
• Spermine 8%
• Electrophoretic Mobility Shift Assay 7%
• Gene Expression 3%
• Therapeutics 2%

Chemical Compounds

• L-Lysine 47%
• Pyrimidine 34%
• Copolymer 25%
• Thermodynamics 23%
• pH Value 16%
• Spermine 9%
• Isothermal Titration Calorimetry 8%
• Kinetics Type 7%
• Kd 5%
• Time 5%
• Dissociation 5%
• Application 2%