Polymorphism of a Qa‐1‐associated antigen defined by cytotoxic T cells. I. Qed‐1a and Qed‐1d

K. F. Lindahl, B. Hausmann, L. Flaherty

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Tlad mice have a distinct Qed‐1 allele, Qed‐1d. Its product is detected by cytotoxic T cells raised in C57BW6 (H‐2b, Tlab) mice against cells from a new recombinant, B6‐TL.123+ (H‐2b, Tlad/b). Qed‐1d is also found on cells from B10.M, A.CA and B10.STC90 mice. It cross‐reacts weakly with Qed‐1b. (C57BL/6 X BALB/c) F1 anti‐B10. A (SR) effectors discriminate Qed‐1a and Qed‐1d, while C3H/HeJ anti‐B10. BR effectors cross‐react extensively. CB6F1 anti‐5R effector cells also discriminate between the Qed‐1 antigens of B6‐Tlaa (H‐2b, Tlaa) and those of B10. BR and other H‐2k, Tlaa strains.

Original languageEnglish (US)
Pages (from-to)159-166
Number of pages8
JournalEuropean Journal of Immunology
Volume12
Issue number2
DOIs
StatePublished - 1982

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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