Polysomnogram in major depressive and obsessive‐compulsive disorders: A preliminary study

R. Armitage, J. Debus, B. Kiger, M. Trivedi, J. Cain, H. P. Roffwarg, A. J. Rush

Research output: Contribution to journalArticle

5 Scopus citations


The sleep macroarchitecture of 10 outpatients with obsessive‐compulsive disorder (OCD) was compared to a group of symptomatic, unmedicated outpatients with nonpsychotic major depressive disorder (MDD) (n = 10). No group main effects were observed. Gender by group interactions were observed on the amount of wakefulness and total sleep period. Male patients with MDD had the highest amount of wakefulness, whereas female patients with OCD showed the least amount of wakefulness. Of the REM sleep parameters, only the duration of the individual REM periods showed between‐group differences, interacting with gender. Gender main effects were also obtained on the amount of Stage 1 sleep, which was lower among females. REM latency did not differentiate the groups. These findings suggest that selected sleep EEG parameters may differentiate patients with MDD from those with OCD, but that these effects are moderated by gender. Depression 2:291–302 (1994/1995). © 1995 Wiley‐Liss, Inc.

Original languageEnglish (US)
Pages (from-to)297-302
Number of pages6
Issue number6
StatePublished - Jan 1 1994


  • EEG
  • depression
  • gender
  • obsessive‐compulsive disorder
  • sleep

ASJC Scopus subject areas

  • Psychiatry and Mental health

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