PopHist: Inferring population history from the spectrum of allele frequencies

Stephen Wooding

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Summary: PopHist is a computer program that uses the frequency spectrum of alleles to: (a) estimate maximum likelihood parameters describing a population's history; and (b) compare alternative hypotheses about population history using likelihood ratio tests. The program uses the matrix coalescent, a method for calculating theoretical frequency spectra that can be applied to sets of unlinked sites.

Original languageEnglish (US)
Pages (from-to)539-540
Number of pages2
JournalBioinformatics
Volume19
Issue number4
DOIs
StatePublished - Mar 1 2003

ASJC Scopus subject areas

  • Statistics and Probability
  • Biochemistry
  • Molecular Biology
  • Computer Science Applications
  • Computational Theory and Mathematics
  • Computational Mathematics

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