PopHist: Inferring population history from the spectrum of allele frequencies

Stephen Wooding

doi:10.1093/bioinformatics/btg024

PopHist: Inferring population history from the spectrum of allele frequencies

Stephen Wooding

Eugene Mcdermott Center For Human Growth & Development

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Summary: PopHist is a computer program that uses the frequency spectrum of alleles to: (a) estimate maximum likelihood parameters describing a population's history; and (b) compare alternative hypotheses about population history using likelihood ratio tests. The program uses the matrix coalescent, a method for calculating theoretical frequency spectra that can be applied to sets of unlinked sites.

Original language	English (US)
Pages (from-to)	539-540
Number of pages	2
Journal	Bioinformatics
Volume	19
Issue number	4
DOIs	https://doi.org/10.1093/bioinformatics/btg024
State	Published - Mar 1 2003

ASJC Scopus subject areas

Statistics and Probability
Biochemistry
Molecular Biology
Computer Science Applications
Computational Theory and Mathematics
Computational Mathematics

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10.1093/bioinformatics/btg024

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title = "PopHist: Inferring population history from the spectrum of allele frequencies",

abstract = "Summary: PopHist is a computer program that uses the frequency spectrum of alleles to: (a) estimate maximum likelihood parameters describing a population's history; and (b) compare alternative hypotheses about population history using likelihood ratio tests. The program uses the matrix coalescent, a method for calculating theoretical frequency spectra that can be applied to sets of unlinked sites.",

author = "Stephen Wooding",

note = "Funding Information: The author was supported by a NIH Genome Sciences (Genome Informatics) Training Grant to the University of Utah.",

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N2 - Summary: PopHist is a computer program that uses the frequency spectrum of alleles to: (a) estimate maximum likelihood parameters describing a population's history; and (b) compare alternative hypotheses about population history using likelihood ratio tests. The program uses the matrix coalescent, a method for calculating theoretical frequency spectra that can be applied to sets of unlinked sites.

AB - Summary: PopHist is a computer program that uses the frequency spectrum of alleles to: (a) estimate maximum likelihood parameters describing a population's history; and (b) compare alternative hypotheses about population history using likelihood ratio tests. The program uses the matrix coalescent, a method for calculating theoretical frequency spectra that can be applied to sets of unlinked sites.

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PopHist: Inferring population history from the spectrum of allele frequencies

Abstract

ASJC Scopus subject areas

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