PopHist: Inferring population history from the spectrum of allele frequencies

Stephen Wooding

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Summary: PopHist is a computer program that uses the frequency spectrum of alleles to: (a) estimate maximum likelihood parameters describing a population's history; and (b) compare alternative hypotheses about population history using likelihood ratio tests. The program uses the matrix coalescent, a method for calculating theoretical frequency spectra that can be applied to sets of unlinked sites.

Original languageEnglish (US)
Pages (from-to)539-540
Number of pages2
JournalBioinformatics
Volume19
Issue number4
DOIs
StatePublished - Mar 1 2003

Fingerprint

Frequency Spectrum
Gene Frequency
Maximum likelihood
Computer program listings
Likelihood Functions
Likelihood Ratio Test
Maximum Likelihood Estimate
Population
Software
Alternatives
History

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Computer Science Applications
  • Computational Theory and Mathematics

Cite this

PopHist : Inferring population history from the spectrum of allele frequencies. / Wooding, Stephen.

In: Bioinformatics, Vol. 19, No. 4, 01.03.2003, p. 539-540.

Research output: Contribution to journalArticle

Wooding, Stephen. / PopHist : Inferring population history from the spectrum of allele frequencies. In: Bioinformatics. 2003 ; Vol. 19, No. 4. pp. 539-540.
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