Population-based precision cancer screening: A symposium on evidence, epidemiology, and next steps

Pamela M. Marcus, Nora Pashayan, Timothy R. Church, V. Paul Doria-Rose, Michael K. Gould, Rebecca A. Hubbard, Michael Marrone, Diana L. Miglioretti, Paul D. Pharoah, Paul F. Pinsky, Katherine A. Rendle, Hilary A. Robbins, Megan C. Roberts, Betsy Rolland, Mark Schiffman, Jasmin A. Tiro, Ann G. Zauber, Deborah M. Winn, Muin J. Khoury

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Precision medicine, an emerging approach for disease treatment that takes into account individual variability in genes, environment, and lifestyle, is under consideration for preventive interventions, including cancer screening. On September 29, 2015, the National Cancer Institute sponsored a symposium entitled "Precision Cancer Screening in the General Population: Evidence, Epidemiology, and Next Steps". The goal was two-fold: to share current information on the evidence, practices, and challenges surrounding precision screening for breast, cervical, colorectal, lung, and prostate cancers, and to allow for in-depth discussion among experts in relevant fields regarding how epidemiology and other population sciences can be used to generate evidence to inform precision screening strategies. Attendees concluded that the strength of evidence for efficacy and effectiveness of precision strategies varies by cancer site, that no one research strategy or methodology would be able or appropriate to address the many knowledge gaps in precision screening, and that issues surrounding implementation must be researched as well. Additional discussion needs to occur to identify the high priority research areas in precision cancer screening for pertinent organs and to gather the necessary evidence to determine whether further implementation of precision cancer screening strategies in the general population would be feasible and beneficial.

Original languageEnglish (US)
Pages (from-to)1449-1455
Number of pages7
JournalCancer Epidemiology Biomarkers and Prevention
Volume25
Issue number11
DOIs
StatePublished - Nov 1 2016

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Early Detection of Cancer
Epidemiology
Population
Precision Medicine
National Cancer Institute (U.S.)
Research
Uterine Cervical Neoplasms
Life Style
Colorectal Neoplasms
Lung Neoplasms
Prostatic Neoplasms
Breast Neoplasms
Genes
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Epidemiology
  • Oncology

Cite this

Marcus, P. M., Pashayan, N., Church, T. R., Doria-Rose, V. P., Gould, M. K., Hubbard, R. A., ... Khoury, M. J. (2016). Population-based precision cancer screening: A symposium on evidence, epidemiology, and next steps. Cancer Epidemiology Biomarkers and Prevention, 25(11), 1449-1455. https://doi.org/10.1158/1055-9965.EPI-16-0555

Population-based precision cancer screening : A symposium on evidence, epidemiology, and next steps. / Marcus, Pamela M.; Pashayan, Nora; Church, Timothy R.; Doria-Rose, V. Paul; Gould, Michael K.; Hubbard, Rebecca A.; Marrone, Michael; Miglioretti, Diana L.; Pharoah, Paul D.; Pinsky, Paul F.; Rendle, Katherine A.; Robbins, Hilary A.; Roberts, Megan C.; Rolland, Betsy; Schiffman, Mark; Tiro, Jasmin A.; Zauber, Ann G.; Winn, Deborah M.; Khoury, Muin J.

In: Cancer Epidemiology Biomarkers and Prevention, Vol. 25, No. 11, 01.11.2016, p. 1449-1455.

Research output: Contribution to journalArticle

Marcus, PM, Pashayan, N, Church, TR, Doria-Rose, VP, Gould, MK, Hubbard, RA, Marrone, M, Miglioretti, DL, Pharoah, PD, Pinsky, PF, Rendle, KA, Robbins, HA, Roberts, MC, Rolland, B, Schiffman, M, Tiro, JA, Zauber, AG, Winn, DM & Khoury, MJ 2016, 'Population-based precision cancer screening: A symposium on evidence, epidemiology, and next steps', Cancer Epidemiology Biomarkers and Prevention, vol. 25, no. 11, pp. 1449-1455. https://doi.org/10.1158/1055-9965.EPI-16-0555
Marcus, Pamela M. ; Pashayan, Nora ; Church, Timothy R. ; Doria-Rose, V. Paul ; Gould, Michael K. ; Hubbard, Rebecca A. ; Marrone, Michael ; Miglioretti, Diana L. ; Pharoah, Paul D. ; Pinsky, Paul F. ; Rendle, Katherine A. ; Robbins, Hilary A. ; Roberts, Megan C. ; Rolland, Betsy ; Schiffman, Mark ; Tiro, Jasmin A. ; Zauber, Ann G. ; Winn, Deborah M. ; Khoury, Muin J. / Population-based precision cancer screening : A symposium on evidence, epidemiology, and next steps. In: Cancer Epidemiology Biomarkers and Prevention. 2016 ; Vol. 25, No. 11. pp. 1449-1455.
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