Porcine pulmonary artery distension during static pressure inflation

Yik Ching Lee, Alys Clark, Matthew Fuld, Susan Haynes, Abhay Divekar, Eric Hoffman, Merryn Tawhai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

To improve the definition of the geometrical and mechanical properties of the porcine pulmonary arteries, we utilized an in vivo imaging-based approach to quantify the influence of static extravascular pressure change on pulmonary arterial geometry. The cross-sectional area and distance from the inlet of pulmonary arteries of two animals were measured over a range of static airway inflation pressure (7 cmH2O - 25 cmH2O, i.e. 0.69 kPa - 2.45 kPa). Vessels with diameter range of approximately 2.0 mm to 5.5 mm at airway inflation pressure of 25 cmH2O (2.45kPa) were considered. The results suggest that lung inflation stretches the vessels laterally, but has no statistically significant effect on diameter.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2013
Subtitle of host publicationBiomedical Applications in Molecular, Structural, and Functional Imaging
DOIs
StatePublished - 2013
Externally publishedYes
EventMedical Imaging 2013: Biomedical Applications in Molecular, Structural, and Functional Imaging - Lake Buena Vista, FL, United States
Duration: Feb 10 2013Feb 13 2013

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8672
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2013: Biomedical Applications in Molecular, Structural, and Functional Imaging
Country/TerritoryUnited States
CityLake Buena Vista, FL
Period2/10/132/13/13

Keywords

  • Artery distensibility
  • CTPA image analysis
  • Porcine

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging
  • Biomaterials

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