Vozmozhnyǐ mekhanizm sliiania membran.

Translated title of the contribution: Possible mechanism of membrane fusion

M. M. Kozlov, V. S. Markin

Research output: Contribution to journalArticle

130 Scopus citations

Abstract

The stalker mechanism of membrane fusion was considered. Initiation and evolution of monolayer and bilayer bridges-stalks between the membranes were studied. From the expression of elastic energy of the stalk the value of spontaneous curvature of its membrane Ks at which the bridge may appear, was found. It was shown that in terms of the stalker mechanism formation of the stalk of the final radius or complete fusion were possible Ks values for realizing this or that variant were found. The energetic barrier of hydrophobic interaction and the barrier of elastic energy which the membranes had to overcome for stalker formation were found. The experimental data on the fusion of small and large liposomes were analysed.

Original languageRussian
Pages (from-to)242-247
Number of pages6
JournalBiofizika
Volume28
Issue number2
StatePublished - Mar 1 1983

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Kozlov, M. M., & Markin, V. S. (1983). Vozmozhnyǐ mekhanizm sliiania membran. Biofizika, 28(2), 242-247.