TY - JOUR
T1 - Post-thrombotic syndrome is uncommon in childhood cancer survivors
AU - Journeycake, Janna M.
AU - Eshelman, Debra
AU - Buchanan, George R.
PY - 2006/2
Y1 - 2006/2
N2 - Deep vein thrombosis occurs in up to 50% of children with tunneled central venous catheters (CVCs). CVC-related deep vein thrombosis involving the upper extremity is usually asymptomatic but can result in post-thrombotic syndrome (swelling, pain, skin changes, and functional impairment). In a cohort of childhood cancer survivors evaluated clinically a mean of 7.5 ± 2.8 years after completion of therapy who previously had CVCs in place for a median 15.5 months, none of 50 patients (95% CI ∇ 0% to 6%) had these features diagnostic of post-thrombotic syndrome. Five patients had arm circumference 3% to 5% greater ipsilateral to the prior CVC.
AB - Deep vein thrombosis occurs in up to 50% of children with tunneled central venous catheters (CVCs). CVC-related deep vein thrombosis involving the upper extremity is usually asymptomatic but can result in post-thrombotic syndrome (swelling, pain, skin changes, and functional impairment). In a cohort of childhood cancer survivors evaluated clinically a mean of 7.5 ± 2.8 years after completion of therapy who previously had CVCs in place for a median 15.5 months, none of 50 patients (95% CI ∇ 0% to 6%) had these features diagnostic of post-thrombotic syndrome. Five patients had arm circumference 3% to 5% greater ipsilateral to the prior CVC.
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U2 - 10.1016/j.jpeds.2005.09.033
DO - 10.1016/j.jpeds.2005.09.033
M3 - Article
C2 - 16492443
AN - SCOPUS:33645832350
SN - 0022-3476
VL - 148
SP - 275
EP - 277
JO - Journal of Pediatrics
JF - Journal of Pediatrics
IS - 2
ER -