Posterior Urethral Valves

Irina Stanasel, Edmond Gonzales

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Posterior urethral valves (PUV) are the most common cause of lower urinary tract obstruction in male infants. Due to improved technique and availability of prenatal imaging, diagnosis is typically suspected prenatally and confirmed postnatally. Prenatal intervention is performed in select centers with vesicoamniotic shunting or with fetal cystoscopy and antegrade ablation of the PUV when detected. Prenatal intervention has been associated with an improvement in neonatal survival; however, evidence that renal function is indeed improved remains scant. The mainstay of treatment remains early diagnosis with early establishment of drainage and subsequent management of bladder dysfunction with behavioral therapy, medication, clean intermittent catheterization, and occasionally with bladder augmentation. Other measures such as nephrectomy can be implemented to manage polyuria. Ultimately, 30 % of patients born with PUV develop end-stage renal disease and require renal transplantation.

Original languageEnglish (US)
Pages (from-to)250-255
Number of pages6
JournalCurrent Bladder Dysfunction Reports
Volume10
Issue number3
DOIs
StatePublished - Sep 1 2015

Fingerprint

Urinary Bladder
Intermittent Urethral Catheterization
Polyuria
Cystoscopy
Ablation
Nephrectomy
Prenatal Diagnosis
Urinary Tract
Kidney Transplantation
Drainage
Chronic Kidney Failure
Early Diagnosis
Availability
Kidney
Imaging techniques
Survival
Therapeutics

Keywords

  • Fetal intervention
  • Hydronephrosis
  • Lower urinary tract obstruction
  • Pediatric renal transplant
  • Posterior urethral valves

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology

Cite this

Posterior Urethral Valves. / Stanasel, Irina; Gonzales, Edmond.

In: Current Bladder Dysfunction Reports, Vol. 10, No. 3, 01.09.2015, p. 250-255.

Research output: Contribution to journalReview article

Stanasel, Irina ; Gonzales, Edmond. / Posterior Urethral Valves. In: Current Bladder Dysfunction Reports. 2015 ; Vol. 10, No. 3. pp. 250-255.
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