Postoperative Elevated Resistive Indices Do Not Predict Hepatic Artery Thrombosis in Extended Criteria Donor Livers

Eric J. Siskind, Fauzia Vandermeer, Tamar R. Siskind, David A. Bruno, Samuel Sultan, Josue Alvarez-Casas, Arielle Stafford, Barton Lane, John C. Lamattina, Rolf N. Barth, Steven I. Hanish

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Postoperative transplant liver ultrasounds were analyzed in standard criteria donor (SCD), extended criteria donor (ECD), and donation after cardiac death (DCD) liver allografts to determine if elevated resistive indices (RIs) are consistently present and if they are pathological. Postoperative transplant liver ultrasounds were reviewed from 115 consecutive patients. Hepatic arterial RIs were stratified based on the type of donor: DCD, macrosteatosis (>30%), or standard criteria. In all patients with elevated RI, subsequent ultrasounds were reviewed to demonstrate RI normalization. The mean RI for all 115 patients was 0.64, DCD was 0.67, macrosteatosis was 0.81, and SCD was 0.61 (p = 0.033). The RI on subsequent liver ultrasounds for DCD and macrosteatosis normalized without any intervention. There were no incidences of early hepatic artery thrombosis (HAT) observed in the cohort. Hepatic arterial RI in ECDs and DCDs are elevated in the immediate postoperative period but are not predictive of HAT. It represents interparenchymal graft stiffness and overall graft edema rather than an impending technical complication. The results of our study do not support the routine use of anticoagulation or routine investigation with computed tomography angiography for elevated RIs as these findings are self-limiting and normalize over a short period of time. We hope that this information helps guide the clinical management of liver transplant patients from expanded criteria donors.

Original languageEnglish (US)
Pages (from-to)238-240
Number of pages3
JournalInternational Journal of Angiology
Volume26
Issue number4
DOIs
StatePublished - Dec 1 2017
Externally publishedYes

Keywords

  • donation after cardiac death
  • extended criteria donors
  • hepatic artery thrombosis
  • hepatic macrosteatosis
  • liver transplant ultrasound
  • liver transplantation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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  • Cite this

    Siskind, E. J., Vandermeer, F., Siskind, T. R., Bruno, D. A., Sultan, S., Alvarez-Casas, J., Stafford, A., Lane, B., Lamattina, J. C., Barth, R. N., & Hanish, S. I. (2017). Postoperative Elevated Resistive Indices Do Not Predict Hepatic Artery Thrombosis in Extended Criteria Donor Livers. International Journal of Angiology, 26(4), 238-240. https://doi.org/10.1055/s-0037-1598623