Postpartum thyroid measures and depressive symptomology: A pilot study

Sarah J. Breese McCoy, J. Martin Beal, Mark E. Payton, Audra L. Stewart, Ariana M. DeMers, Gary H. Watson

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Context: While correlations have been demonstrated between postpartum depression and psychosocial and circumstantial risk factors, some evidence exists for a similar relationship between postpartum depression and thyroid measures. Objective: To search at 4 weeks postpartum for correlations of numerical scores on a postnatal depression screening tool and thyroid measures. Methods: Subjects took the Edinburgh Postnatal Depression Scale (EPDS) prenatally and at 4 weeks postpartum. Participants were also given blood tests for thyroid-stimulating hormone (TSH), free thyroxine4, thyroid peroxidase, and thyroglobulin at the same testing intervals. Results: Fifty-one subjects aged 18 years or older were recruited. Subjects with higher serum TSH at 4 weeks post-partum tended to have higher EPDS scores. Similarly, the 7 subjects (13.7%) with positive postnatal thyroid antibody tests were more likely than their counterparts to have higher EPDS scores. Conclusions: Presence of thyroid autoantibodies or higher TSH levels during the postpartum period may be related to depressive symptoms or dysphoric mood, even when clinical depression is not present. Either or both of these associations may contribute, along with other physiologic and psychosocial risk factors, to postpartum depression. (ClinicalTrials.gov number NCT00565032).

Original languageEnglish (US)
Pages (from-to)503-507
Number of pages5
JournalJournal of the American Osteopathic Association
Volume108
Issue number9
StatePublished - Sep 2008

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Postpartum Depression
Postpartum Period
Thyroid Gland
Thyrotropin
Depression
Iodide Peroxidase
Thyroglobulin
Hematologic Tests
Autoantibodies
Psychology
Antibodies
Serum

ASJC Scopus subject areas

  • Complementary and alternative medicine

Cite this

Breese McCoy, S. J., Beal, J. M., Payton, M. E., Stewart, A. L., DeMers, A. M., & Watson, G. H. (2008). Postpartum thyroid measures and depressive symptomology: A pilot study. Journal of the American Osteopathic Association, 108(9), 503-507.

Postpartum thyroid measures and depressive symptomology : A pilot study. / Breese McCoy, Sarah J.; Beal, J. Martin; Payton, Mark E.; Stewart, Audra L.; DeMers, Ariana M.; Watson, Gary H.

In: Journal of the American Osteopathic Association, Vol. 108, No. 9, 09.2008, p. 503-507.

Research output: Contribution to journalArticle

Breese McCoy, SJ, Beal, JM, Payton, ME, Stewart, AL, DeMers, AM & Watson, GH 2008, 'Postpartum thyroid measures and depressive symptomology: A pilot study', Journal of the American Osteopathic Association, vol. 108, no. 9, pp. 503-507.
Breese McCoy SJ, Beal JM, Payton ME, Stewart AL, DeMers AM, Watson GH. Postpartum thyroid measures and depressive symptomology: A pilot study. Journal of the American Osteopathic Association. 2008 Sep;108(9):503-507.
Breese McCoy, Sarah J. ; Beal, J. Martin ; Payton, Mark E. ; Stewart, Audra L. ; DeMers, Ariana M. ; Watson, Gary H. / Postpartum thyroid measures and depressive symptomology : A pilot study. In: Journal of the American Osteopathic Association. 2008 ; Vol. 108, No. 9. pp. 503-507.
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