Postural Orthostatic Tachycardia Syndrome: JACC Focus Seminar

Research output: Contribution to journalReview articlepeer-review

80 Scopus citations


Postural orthostatic tachycardia syndrome (POTS), the most common form of orthostatic intolerance in young people, affects approximately 500,000 people in the United States alone, typically young women at the peak of their education and the beginning of their working lives. This is a heterogeneous disorder, the pathophysiology and mechanisms of which are not well understood. There are multiple contributing factors and numerous potential mimics. This review details the most current views on the potential causes, comorbid conditions, proposed subtypes, differential diagnoses, evaluations, and treatment of POTS from cardiological and neurological perspectives.

Original languageEnglish (US)
Pages (from-to)1207-1228
Number of pages22
JournalJournal of the American College of Cardiology
Issue number10
StatePublished - Mar 19 2019


  • POTS
  • orthostatic intolerance
  • postural orthostatic tachycardia syndrome
  • syncope
  • tachycardia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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