TY - JOUR
T1 - Potassium channels in aortic microsomes
T2 - conductance, selectivity, barium-induced blockage and subconductance states
AU - Bezprozvanny, Ilya B.
AU - Benevolensky, Dmitry S.
AU - Naumov, Alexander P.
PY - 1991/4/26
Y1 - 1991/4/26
N2 - The activity of potassium channels of canine aortic sarcoplasmic reticulum was measured using the planar lipid bilayer-fusion technique. The channels have a conductance of 208 pS ( 400 100 mM K+ in cis/trans solutions) and potassium-to-sodium permeability ratio of 7.7. Ba2+ ions produced two main effects: one is the interruption of channel currents for tens to hundreds of milliseconds in a voltage-dependent manner, and the other is the appearance of a second conductance level with amplitude about 60% of the main level.
AB - The activity of potassium channels of canine aortic sarcoplasmic reticulum was measured using the planar lipid bilayer-fusion technique. The channels have a conductance of 208 pS ( 400 100 mM K+ in cis/trans solutions) and potassium-to-sodium permeability ratio of 7.7. Ba2+ ions produced two main effects: one is the interruption of channel currents for tens to hundreds of milliseconds in a voltage-dependent manner, and the other is the appearance of a second conductance level with amplitude about 60% of the main level.
KW - (Canine aorta)
KW - Barium ion blockage
KW - Bilayer
KW - Conductance level
KW - Microsome
KW - Potassium ion channel
KW - Sarcoplasmic reticulum
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U2 - 10.1016/0005-2736(91)90413-3
DO - 10.1016/0005-2736(91)90413-3
M3 - Article
C2 - 2025637
AN - SCOPUS:0025809310
VL - 1064
SP - 75
EP - 80
JO - Biochimica et Biophysica Acta - Biomembranes
JF - Biochimica et Biophysica Acta - Biomembranes
SN - 0005-2736
IS - 1
ER -