Potassium Supplementation of Diuretic Therapy: Pro and Con

Jeen R.e. Haalboom, Albert Struyvenberg, Thomas G. Kelsey, Norman M Kaplan, Richard D. Moore, George D. Webb, Jerome P. Kassirer, John T. Harrington

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Abstract

To the Editor: In the March 21 issue Kaplan et al.1 report that in 16 hypertensive patients with diuretic-induced hypokalemia, potassium chloride supplements, 60 mmol per day, increased the mean serum potassium concentration by 0.56 mmol per liter. We have reason to doubt the general validity of this observation. Potassium chloride supplementation in diuretic-induced hypokalemia has been extensively studied. In one of these studies,2 done in six elderly patients, the administration of 48 mmol of slow-release potassium chloride per day did not significantly raise either plasma or total body potassium (measured as 42K). In a study in 18 patients with.

Original languageEnglish (US)
Pages (from-to)1021-1023
Number of pages3
JournalNew England Journal of Medicine
Volume313
Issue number16
DOIs
Publication statusPublished - Oct 17 1985

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Haalboom, J. R. E., Struyvenberg, A., Kelsey, T. G., Kaplan, N. M., Moore, R. D., Webb, G. D., ... Harrington, J. T. (1985). Potassium Supplementation of Diuretic Therapy: Pro and Con. New England Journal of Medicine, 313(16), 1021-1023. https://doi.org/10.1056/NEJM198510173131613