Potential etiologic role of brushite in the formation of calcium (renal) stones

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Brushite may play an important regulatory role in the formation of calcium -containing renal stones. The urinary environment from patients with hypercalciuric nephrolithiasis is typically supersaturated and shows an increased propensity for the spontaneous nucleation of brushite. Brushite has been identified in "stone-forming" urine and in stones. This crystalline phase may undergo phase transformation to hydroxyapatite or cause heterogeneous nucleation or epitaxial growth of calcium oxalate. Thus, brushite may also participate in the formation of stones of hydroxypatite or calcium oxalate.

Original languageEnglish (US)
Pages (from-to)202-208
Number of pages7
JournalJournal of Crystal Growth
Volume53
Issue number1
DOIs
StatePublished - May 1 1981

Fingerprint

calcium
Calcium
rocks
Calcium Oxalate
Nucleation
oxalates
nucleation
Hydroxyapatite
Epitaxial growth
urine
Durapatite
Phase transitions
Crystalline materials
phase transformations
dibasic calcium phosphate dihydrate
causes

ASJC Scopus subject areas

  • Condensed Matter Physics

Cite this

Potential etiologic role of brushite in the formation of calcium (renal) stones. / Pak, Charles Y C.

In: Journal of Crystal Growth, Vol. 53, No. 1, 01.05.1981, p. 202-208.

Research output: Contribution to journalArticle

@article{a7a67657e0da47bdb97b277a8e988392,
title = "Potential etiologic role of brushite in the formation of calcium (renal) stones",
abstract = "Brushite may play an important regulatory role in the formation of calcium -containing renal stones. The urinary environment from patients with hypercalciuric nephrolithiasis is typically supersaturated and shows an increased propensity for the spontaneous nucleation of brushite. Brushite has been identified in {"}stone-forming{"} urine and in stones. This crystalline phase may undergo phase transformation to hydroxyapatite or cause heterogeneous nucleation or epitaxial growth of calcium oxalate. Thus, brushite may also participate in the formation of stones of hydroxypatite or calcium oxalate.",
author = "Pak, {Charles Y C}",
year = "1981",
month = "5",
day = "1",
doi = "10.1016/0022-0248(81)90066-X",
language = "English (US)",
volume = "53",
pages = "202--208",
journal = "Journal of Crystal Growth",
issn = "0022-0248",
publisher = "Elsevier",
number = "1",

}

TY - JOUR

T1 - Potential etiologic role of brushite in the formation of calcium (renal) stones

AU - Pak, Charles Y C

PY - 1981/5/1

Y1 - 1981/5/1

N2 - Brushite may play an important regulatory role in the formation of calcium -containing renal stones. The urinary environment from patients with hypercalciuric nephrolithiasis is typically supersaturated and shows an increased propensity for the spontaneous nucleation of brushite. Brushite has been identified in "stone-forming" urine and in stones. This crystalline phase may undergo phase transformation to hydroxyapatite or cause heterogeneous nucleation or epitaxial growth of calcium oxalate. Thus, brushite may also participate in the formation of stones of hydroxypatite or calcium oxalate.

AB - Brushite may play an important regulatory role in the formation of calcium -containing renal stones. The urinary environment from patients with hypercalciuric nephrolithiasis is typically supersaturated and shows an increased propensity for the spontaneous nucleation of brushite. Brushite has been identified in "stone-forming" urine and in stones. This crystalline phase may undergo phase transformation to hydroxyapatite or cause heterogeneous nucleation or epitaxial growth of calcium oxalate. Thus, brushite may also participate in the formation of stones of hydroxypatite or calcium oxalate.

UR - http://www.scopus.com/inward/record.url?scp=0001565498&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0001565498&partnerID=8YFLogxK

U2 - 10.1016/0022-0248(81)90066-X

DO - 10.1016/0022-0248(81)90066-X

M3 - Article

VL - 53

SP - 202

EP - 208

JO - Journal of Crystal Growth

JF - Journal of Crystal Growth

SN - 0022-0248

IS - 1

ER -