Precision medicine for multiple sclerosis promotes preventative medicine

Madison R. Hansen, Darin T. Okuda

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Multiple sclerosis (MS) is a chronic, lifelong disease, currently without a cure that is responsible for significant neurological injury in young adults. Precision medicine for MS aims to provide a more exacting and refined approach toward management by providing recommendations based on disease subtype, clinical status, existing radiological data, para-clinical data, and other biological markers. To achieve better outcomes, the three stages of care—diagnosis, treatment, and management—should be optimized. However, as the temporal profile of disease behavior is highly variable in MS, and unlike outcomes from other chronic conditions (i.e., hypertension, diabetes mellitus, etc.), should precision medicine for MS be one that focuses more on disease prevention and lifestyle modifications beyond recommendations for the use of disease-modifying therapies? As scientific advancements continue within the field of neuroimmunology, and until reliable biomarkers that predict disease outcomes are available, success may be better achieved by focusing on modifiable factors to reduce future disability.

Original languageEnglish (US)
Pages (from-to)62-71
Number of pages10
JournalAnnals of the New York Academy of Sciences
Volume1420
Issue number1
DOIs
StatePublished - May 1 2018

Keywords

  • diagnosis
  • management
  • multiple sclerosis
  • precision
  • preventative
  • treatment

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

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