Precision medicine in allergic disease-food allergy, drug allergy, and anaphylaxis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma and Immunology

A. Muraro, R. F. Lemanske, M. Castells, M. J. Torres, D. Khan, H. U. Simon, C. Bindslev-Jensen, W. Burks, L. K. Poulsen, H. A. Sampson, M. Worm, K. C. Nadeau

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

This consensus document summarizes the current knowledge on the potential for precision medicine in food allergy, drug allergy, and anaphylaxis under the auspices of the PRACTALL collaboration platform. PRACTALL is a joint effort of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma and Immunology, which aims to synchronize the European and American approaches to allergy care. Precision medicine is an emerging approach for disease treatment based on disease endotypes, which are phenotypic subclasses associated with specific mechanisms underlying the disease. Although significant progress has been made in defining endotypes for asthma, definitions of endotypes for food and drug allergy or for anaphylaxis lag behind. Progress has been made in discovery of biomarkers to guide a precision medicine approach to treatment of food and drug allergy, but further validation and quantification of these biomarkers are needed to allow their translation into practice in the clinical management of allergic disease. Copyright

Original languageEnglish (US)
JournalAllergy: European Journal of Allergy and Clinical Immunology
DOIs
StateAccepted/In press - 2017

Fingerprint

Drug Hypersensitivity
Precision Medicine
Food Hypersensitivity
Anaphylaxis
Allergy and Immunology
Biomarkers
Disease Management
Hypersensitivity
Asthma
Therapeutics

Keywords

  • Allergy
  • Anaphylaxis
  • Endotype
  • Phenotype
  • Precision medicine

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Precision medicine in allergic disease-food allergy, drug allergy, and anaphylaxis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma and Immunology. / Muraro, A.; Lemanske, R. F.; Castells, M.; Torres, M. J.; Khan, D.; Simon, H. U.; Bindslev-Jensen, C.; Burks, W.; Poulsen, L. K.; Sampson, H. A.; Worm, M.; Nadeau, K. C.

In: Allergy: European Journal of Allergy and Clinical Immunology, 2017.

Research output: Contribution to journalArticle

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