Predictors of Mortality in Acute Ischemic Stroke Intervention: Analysis of the North American Solitaire Acute Stroke Registry

Italo Linfante, Gail R. Walker, Alicia C. Castonguay, Guilherme Dabus, Amy K. Starosciak, Albert J. Yoo, Alex Abou-Chebl, Gavin W. Britz, Franklin A. Marden, Alexandria Alvarez, Rishi Gupta, Chun Huan J Sun, Coleman Martin, William E. Holloway, Nils Mueller-Kronast, Joey D. English, Tim W. Malisch, Hormozd Bozorgchami, Andrew Xavier, Ansaar T. RaiMichael T. Froehler, Aamir Badruddin, Thanh N. Nguyen, M. Asif Taqi, Michael G. Abraham, Vallabh Janardhan, Hashem Shaltoni, Roberta Novakovic, Peng R. Chen, Ritesh Kaushal, Ashish Nanda, Mohammad A. Issa, Raul G. Nogueira, Osama O. Zaidat

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

BACKGROUND AND PURPOSE: Failure to recanalize predicts mortality in acute ischemic stroke. In the North American Solitaire Acute Stroke registry, we investigated parameters associated with mortality in successfully recanalized patients.

METHODS: Logistic regression was used to evaluate baseline characteristics and recanalization parameters for association with 90-day mortality. A multivariable model was developed based on backward selection with retention criteria of P

RESULTS: Successfully recanalized patients had lower mortality (25.2% [59/234] versus 46.9% [38/81] P

CONCLUSIONS: Failure to recanalize and presence of symptomatic intracranial hemorrhage resulted in increased mortality. Despite successful recanalization, proximal occlusion, high National Institutes of Health Stroke Scale, and need for rescue therapy were predictors of mortality.

Original languageEnglish (US)
Pages (from-to)2305-2308
Number of pages4
JournalStroke; a journal of cerebral circulation
Volume46
Issue number8
DOIs
StatePublished - Aug 1 2015

Keywords

  • carotid artery, internal
  • intracra
  • mortality
  • nial hemorrhages
  • stroke
  • thrombectomy

ASJC Scopus subject areas

  • Medicine(all)

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    Linfante, I., Walker, G. R., Castonguay, A. C., Dabus, G., Starosciak, A. K., Yoo, A. J., Abou-Chebl, A., Britz, G. W., Marden, F. A., Alvarez, A., Gupta, R., Sun, C. H. J., Martin, C., Holloway, W. E., Mueller-Kronast, N., English, J. D., Malisch, T. W., Bozorgchami, H., Xavier, A., ... Zaidat, O. O. (2015). Predictors of Mortality in Acute Ischemic Stroke Intervention: Analysis of the North American Solitaire Acute Stroke Registry. Stroke; a journal of cerebral circulation, 46(8), 2305-2308. https://doi.org/10.1161/STROKEAHA.115.009530