Pregnancy complicated by hemoglobin CC and C-β-thalassemia disease

M. C. Maberry, R. A. Mason, F. G. Cunningham, J. A. Pritchard

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The outcomes of 72 pregnancies in 20 women with either hemoglobin CC or C-β-thalassemia are described. Except for mild to moderate hemolytic anemia, maternal complications caused by the hemoglobinopathy were infrequent and perinatal outcomes were generally good. In eight women, blood volume expansion determined by 51Cr chromium-tagged erythrocytes was similar to that for normally pregnant women. Mean red-cell survival was determined 11 times in eight women, and the red-cell half-life of 22 days was significantly shorter than that of 35 days for normally pregnant women.

Original languageEnglish (US)
Pages (from-to)324-327
Number of pages4
JournalObstetrics and Gynecology
Volume76
Issue number3 I
StatePublished - 1990

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Hemoglobin C
Thalassemia
Pregnancy
Pregnant Women
Hemoglobinopathies
Hemolytic Anemia
Chromium
Pregnancy Outcome
Blood Volume
Half-Life
Cell Survival
Hemoglobins
Erythrocytes
Mothers

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Maberry, M. C., Mason, R. A., Cunningham, F. G., & Pritchard, J. A. (1990). Pregnancy complicated by hemoglobin CC and C-β-thalassemia disease. Obstetrics and Gynecology, 76(3 I), 324-327.

Pregnancy complicated by hemoglobin CC and C-β-thalassemia disease. / Maberry, M. C.; Mason, R. A.; Cunningham, F. G.; Pritchard, J. A.

In: Obstetrics and Gynecology, Vol. 76, No. 3 I, 1990, p. 324-327.

Research output: Contribution to journalArticle

Maberry, MC, Mason, RA, Cunningham, FG & Pritchard, JA 1990, 'Pregnancy complicated by hemoglobin CC and C-β-thalassemia disease', Obstetrics and Gynecology, vol. 76, no. 3 I, pp. 324-327.
Maberry, M. C. ; Mason, R. A. ; Cunningham, F. G. ; Pritchard, J. A. / Pregnancy complicated by hemoglobin CC and C-β-thalassemia disease. In: Obstetrics and Gynecology. 1990 ; Vol. 76, No. 3 I. pp. 324-327.
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