Pregnancy complicated by hereditary spherocytosis

M. C. Maberry, R. A. Mason, F. G. Cunningham, J. A. Pritchard

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Hereditary spherocytosis is a spectrum of inherited erythrocyte membrane defects that result in hemolysis and varying degrees of anemia. Among 50 pregnancies in 23 women with spherocytosis, maternal complications were infrequent except for anemia, and perinatal outcomes were generally good. In six women, blood volume expansion estimated by51chromium-tagged erythrocytes was similar to that for normal pregnant women. Mean red cell survival measured during seven pregnancies in six women ranged at 30–90 days, consistent with the heterogeneity of this disorder.

Original languageEnglish (US)
Pages (from-to)735-738
Number of pages4
JournalObstetrics and gynecology
Volume79
Issue number5
StatePublished - May 1992

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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